NCT07485257Completed
Molecular Profiling of MRI-PSMA PET Discordance in Prostate Cancer
Molecular Profiling of Prostate Cancer Lesions With MRI-PSMA PET Discordance
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
MRI and PSMA-PET are highly sensitive imaging tools for prostate cancer, yet they often detect different lesions. These discordant findings pose clinical uncertainty because their biological significance is unclear. This project aims to molecularly characterize MRI-PSMA PET discordant lesions using high-quality biobanked samples from patients enrolled in an institutional study (NCT06187870). By integrating imaging and molecular data, the study will clarify whether these lesions represent indolent disease, aggressive subclones, or biologically distinct entities, and will assess their clinical implications.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 30 (actual)
- First submitted
- 10 Dec 2025
- Start date
- 4 Dec 2023
- Primary completion date
- 9 Dec 2025
- Lead sponsor
- IRCCS San Raffaele
- Diseases
- Prostate cancer
- NCT number
- NCT07485257
What you commit to
- Study type: Observational
- Participants enrolled: 30
- From 4 Dec 2023 to the primary completion date, 9 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Low quality samples availability
Who the study is looking for
- Signed informed consent
- PCa diagnosis
- Available samples
- Performed both PSMA PET and MRI
Age in the registry: 18 years to - · Sex: Male
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS San Raffaele Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.