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NCT07485257Completed

Molecular Profiling of MRI-PSMA PET Discordance in Prostate Cancer

Molecular Profiling of Prostate Cancer Lesions With MRI-PSMA PET Discordance

Source: ClinicalTrials.gov · Last updated 15 May 2026

Brief summary (registry, in English)

MRI and PSMA-PET are highly sensitive imaging tools for prostate cancer, yet they often detect different lesions. These discordant findings pose clinical uncertainty because their biological significance is unclear. This project aims to molecularly characterize MRI-PSMA PET discordant lesions using high-quality biobanked samples from patients enrolled in an institutional study (NCT06187870). By integrating imaging and molecular data, the study will clarify whether these lesions represent indolent disease, aggressive subclones, or biologically distinct entities, and will assess their clinical implications.

Status (registry)
Completed
Study type
Observational
Enrollment
30 (actual)
First submitted
10 Dec 2025
Start date
4 Dec 2023
Primary completion date
9 Dec 2025
Lead sponsor
IRCCS San Raffaele
NCT number
NCT07485257

What you commit to

  • Study type: Observational
  • Participants enrolled: 30
  • From 4 Dec 2023 to the primary completion date, 9 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Low quality samples availability

Who the study is looking for

  • Signed informed consent
  • PCa diagnosis
  • Available samples
  • Performed both PSMA PET and MRI

Age in the registry: 18 years to - · Sex: Male

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
IRCCS San Raffaele
Coordinator of this site? Confirm its status
MilanItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.