NCT07487532Not yet recruiting
Acupuncture for Preventing Atrial Arrhythmia Recurrence After Ablation
Effectiveness of Acupuncture for Atrial Tachyarrhythmia Prevention After Catheter Ablation in Persistent Atrial Fibrillation Patients: a Prospective, Open-label, Randomized, Blank-controlled Trial
Source: ClinicalTrials.gov · Last updated 1 Apr 2026
Brief summary (registry, in English)
This study aims to evaluate whether acupuncture can reduce the recurrence of atrial arrhythmias after catheter ablation in patients with persistent atrial fibrillation. Catheter ablation is an effective treatment for atrial fibrillation, but recurrence remains common, especially in persistent cases. In this prospective, randomized, open-label trial, 120 patients with persistent atrial fibrillation who have undergone successful catheter ablation will be enrolled and randomly assigned to two groups. The intervention group will receive acupuncture in addition to standard medical therapy, while the control group will receive standard medical therapy alone. Participants will be followed for 12 months. The primary outcome is the recurrence of atrial arrhythmias, including atrial fibrillation, atrial flutter, or atrial tachycardia. Secondary outcomes include cardiac structure and function, atrial fibrillation burden, and quality of life. This study will provide clinical evidence on whether acupuncture can be an effective adjunctive therapy to improve outcomes after catheter ablation.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 17 Mar 2026
- Start date
- 1 Apr 2026
- Primary completion date
- 30 Apr 2028
- Lead sponsor
- Shanghai Zhongshan Hospital
- Diseases
- Atrial fibrillation
- NCT number
- NCT07487532
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 1 Apr 2026 to the primary completion date, 30 Apr 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cardiovascular events within the past 3 months (including stroke, transient ischemic attack, myocardial infarction, unstable angina, or cardiac surgery)
- Severe valvular heart disease or other significant structural heart disease
- History of pacemaker implantation
- Acupuncture treatment for cardiovascular disease within the past 3 months
Lab values
- Severe comorbid conditions, including:
- Malignant tumors
- Chronic infectious diseases
- Severe renal dysfunction (eGFR \<30 mL/min/1.73 m² or requiring dialysis)
- Moderate to severe liver dysfunction (Child-Pugh class B or C)
- Anemia (hemoglobin \<90 g/L)
- Systemic diseases requiring steroid therapy
- Severe cognitive impairment or dementia
- Alcohol or substance abuse
- Life expectancy \<12 months
- Poor compliance or inability to provide informed consent
Other
- Symptomatic hypotension with systolic blood pressure \<100 mmHg on two consecutive measurements
- Pregnancy, breastfeeding, or planned pregnancy during the study period
- Second- or third-degree atrioventricular block
- Bifascicular or trifascicular block
- Participation in another interventional clinical study
Who the study is looking for
- Age 20 to 75 years
- Persistent atrial fibrillation
- Undergoing first-time catheter ablation with successful restoration of sinus rhythm
- Left atrial diameter \<50 mm
- Able to understand the study and provide written informed consent
Age in the registry: 20 years to 75 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.