NCT07488091Recruiting
Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana
Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana: Non-academic vs Academic Hospital (Pilot Study)
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
The goal of this observational study is to determine the feasibility and effectiveness of initiating a multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital. The main question it aims to answer is: In a before-and-after study design, we will test the hypothesis that multidisciplinary care for pregnant women with SCD in a non-academic hospital will result in a 50% relative risk reduction in mortality compared to the mortality rate in pregnant women with SCD in the same hospital before the multidisciplinary care. Participants will be managed using the academic hospital's multidisciplinary sickle cell disease obstetrics protocol adapted for the non-academic hospital
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 198 (estimated)
- First submitted
- 16 Feb 2026
- Start date
- Jan 2026
- Primary completion date
- Jan 2028
- Lead sponsor
- University of Ghana Medical School
- Diseases
- Sickle cell disease
- NCT number
- NCT07488091
What you commit to
- Study type: Interventional
- Planned participants: 198
- From Jan 2026 to the primary completion date, Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- All pregnant women with sickle cell disease who do not provide informed consent
- All pregnant women with sickle cell disease who are referred for management of acute complications and hospital admission
- All pregnant women with sickle cell disease who are referred for labor and delivery
Other
- All pregnant women with SCD who plan on delivering outside the non-academic hospital and won't be able to adhere to the follow-up procedures during the puerperium (the first six weeks after childbirth)
Who the study is looking for
- Pregnant women with a confirmed laboratory diagnosis of sickle cell disease
- Pregnancy confirmed by a pelvic ultrasound scan
- Pregnancy should be 34 weeks' gestation or less
- Pregnant women should be aged 18 - 45 years
- Pregnant women should be attendants at the non-academic hospital
Age in the registry: 18 years to 45 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Greater Accra Regional Hospital Coordinator of this site? Confirm its status | Accra | Ghana | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.