Sign in

NCT07488624Completed

Survival Prediction After Neoadjuvant Chemoimmunotherapy and Esophagectomy for Esophageal Squamous Cell Carcinoma

Development and Internal Validation of a Clinicopathologic Prognostic Model for Overall Survival in Esophageal Squamous Cell Carcinoma After Neoadjuvant Chemoimmunotherapy and Esophagectomy: A Multicenter Retrospective Cohort Study

Source: ClinicalTrials.gov · Last updated 13 Aug 2026

Brief summary (registry, in English)

The goal of this retrospective observational study is to develop and internally evaluate a prognostic model for overall survival in patients with esophageal squamous cell carcinoma who received neoadjuvant chemoimmunotherapy followed by esophagectomy. Researchers will review existing clinical, pathologic, and follow-up data from 414 patients treated at three medical centers between 2019 and 2025. The study will assess whether routinely available clinicopathologic factors can provide prognostic information beyond postoperative pathologic staging.

Status (registry)
Completed
Study type
Observational
Enrollment
414 (actual)
First submitted
9 Mar 2026
Start date
1 Mar 2026
Primary completion date
1 Jun 2026
Lead sponsor
Sichuan University
NCT number
NCT07488624

What you commit to

  • Study type: Observational
  • Participants enrolled: 414
  • From 1 Mar 2026 to the primary completion date, 1 Jun 2026
  • 3 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of other malignancies Preoperative antitumor therapy other than neoadjuvant chemoimmunotherapy Incomplete clinicopathologic or follow-up data

Who the study is looking for

  • Age 18 to 80 years Histologically confirmed esophageal squamous cell carcinoma Received at least 1 cycle of neoadjuvant chemoimmunotherapy before surgery Underwent subsequent esophagectomy

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (3)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
West China Hospital,Sichuan University
Coordinator of this site? Confirm its status
ChengduChinaUnknown status
Mianzhu People's Hospital (West China Mianzhu Hospital, Sichuan University)
Coordinator of this site? Confirm its status
MianzhuChinaUnknown status
Suining Central Hospital
Coordinator of this site? Confirm its status
SuiningChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.