NCT07488858Completed
Thyroidectomy: Microscopic Versus Conventional
Comparison of Outcomes of Microscopic Versus Conventional Thyroidectomy
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
Despite promising findings from international studies, the use of microscopic thyroidectomy remains limited in local surgical practice, where conventional thyroidectomy is traditionally followed. There is a scarcity of local data evaluating the benefits of MT, and inconsistencies in reported outcomes highlight the need for further research. The lack of standardized protocols and limited surgeon experience with microscopic techniques contribute to hesitation in its adoption. This study aims to address the research gap by providing comparative data on operative time, intraoperative blood loss, and postoperative complications in microscopic versus conventional thyroidectomy in our setting. The findings will aid in determining whether MT should be incorporated into routine surgical practice to improve patient outcomes and reduce postoperative complications.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 74 (actual)
- First submitted
- 15 Mar 2026
- Start date
- 16 Dec 2025
- Primary completion date
- 15 Mar 2026
- Lead sponsor
- Shahida Islam Medical Complex
- Diseases
- Thyroid cancer
- NCT number
- NCT07488858
What you commit to
- Study type: Interventional
- Participants enrolled: 74
- From 16 Dec 2025 to the primary completion date, 15 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of prior thyroid surgery.
- Patients with invasive thyroid carcinoma, anaplastic thyroid carcinoma, or thyroid lymphoma requiring extensive radical surgery.
Other illness
- Patients with pre-existing hypocalcemia or parathyroid disorders.
Lab values
- Patients with severe medical comorbidities, including uncontrolled diabetes (HbA1c \> 8%), chronic kidney disease (eGFR \< 30 mL/min/1.73m²), liver cirrhosis (Child-Pugh class B or C), or coagulopathy (INR \> 1.5 or platelet count \< 50,000/μL), will be excluded from the study.
Other
- Patients with evidence of lateral lymph node metastasis or local invasion on preoperative imaging (ultrasonography or computed tomography).
- Pregnant or lactating women.
Who the study is looking for
- Both Male or female patients.
- Patients aged 18 to 65 years undergoing thyroidectomy for benign or malignant thyroid disease.
- Patients with multinodular goiter, Grave's disease, thyroid carcinoma indicated for surgery based on their workup.
- Candidates scheduled for unilateral lobectomy, subtotal thyroidectomy, or total thyroidectomy.
- Patients with preoperative normal vocal cord mobility confirmed by laryngoscopy.
- Hemodynamically stable patients without significant comorbidities affecting surgery or anesthesia based on ASA classification (Class I-III).
- Patients who provide informed consent to participate in the study.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shaikh Zayed Hospital, Lahore Coordinator of this site? Confirm its status | Lahore | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.