NCT07491029Not yet recruiting
AI-based Customized tDCS for Finger Motor Recovery After Subacute Stroke
A Multi-center, Randomized, Double-blind, Prospective, Superiority Clinical Trial to Evaluate the Safety and Effectiveness of Artificial Intelligence-based Customized Transcranial Direct Current Stimulation Using MR Images for Improving Finger Motor Function in Patients With Finger Paralysis Due to Subacute Stroke
Source: ClinicalTrials.gov · Last updated 24 Mar 2026
Brief summary (registry, in English)
The goal of this clinical study is to evaluate whether AI-based customized transcranial direct current stimulation (tDCS) using MR images is more effective than sham stimulation in improving finger motor function in patients with finger paralysis caused by subacute stroke. The main questions it aims to answer are: * Does AI-based customized tDCS improve finger motor function compared with sham stimulation? * What medical problems or adverse events occur when participants receive AI-based customized tDCS? Researchers will compare AI-based customized tDCS with sham stimulation (a look-alike stimulation that delivers no electrical current) to determine whether the intervention improves finger motor recovery in patients with subacute stroke.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 116 (estimated)
- First submitted
- 16 Mar 2026
- Start date
- 30 Apr 2026
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- NEUROPHET
- Diseases
- Stroke
- NCT number
- NCT07491029
What you commit to
- Study type: Interventional
- Planned participants: 116
- From 30 Apr 2026 to the primary completion date, 31 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of a stimulation device similar to the investigational device or participation in a related clinical study within the past 1 year
Other illness
- History of a condition affecting the function of the paralyzed arm
- Inability to follow instructions or complete the study due to cognitive impairment or aphasia
- Evidence of delirium, confusion, or other disorders of consciousness
- Presence of uncontrolled medical or surgical conditions
- Severe neurological disorders associated with major psychiatric conditions (e.g., major depressive disorder, schizophrenia, bipolar disorder, or dementia)
- History of uncontrolled epilepsy (seizure disorder)
- Contraindications to transcranial direct current stimulation (tDCS), including:
- Scalp disease or metal materials at the electrode attachment site
- Presence of a cardiac pacemaker or cochlear implant
Other
- Participants will be excluded if they meet any of the following criteria:
- Medical contraindications to MRI examination
- Pregnant or breastfeeding women, or those planning pregnancy during the study period
- Individuals judged by the investigator to be medically or ethically unsuitable for participation in this clinical study
Who the study is looking for
- Participants must meet all of the following criteria to be eligible for this clinical trial:
- Adults aged 19 years or older
- Patients with stroke confirmed by brain imaging
- Subacute stroke patients within 2 weeks to 3 months after stroke onset
- Patients with unilateral upper-extremity paralysis
- Upper-extremity Fugl-Meyer Assessment (FMA-UE, maximum score 66) score between 20 and 56
- Participants who voluntarily provide written informed consent after receiving and understanding the study procedures and requirements
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Severance hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.