NCT07492953Completed
Using Enhanced External Counterpulsation to Recover Cardiovascular Function for Patient of Chronic Diseases
Source: ClinicalTrials.gov · Last updated 25 Mar 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn whether enhanced external counterpulsation (EECP) therapy can improve cardiopulmonary function and symptoms in adults with long COVID. It will also evaluate the safety and feasibility of two different EECP treatment schedules. The main questions it aims to answer are: * Does EECP therapy improve functional exercise capacity and cardiopulmonary performance in patients with long COVID? * Do different EECP treatment schedules (standard vs. accelerated sessions) lead to different improvements in symptoms, quality of life, and physiological outcomes? * What side effects or medical problems occur during EECP therapy? Researchers will compare two EECP treatment schedules to determine whether a shorter, accelerated program provides similar benefits to the standard schedule. Participants will: * Receive EECP therapy either 1 hour per day (5 days per week for 7 weeks) or 2 hours per day (5 days per week for about 4 weeks), both totaling 35 hours of treatment * Visit the cardiopulmonary rehabilitation clinic regularly for supervised treatment sessions * Complete physical performance tests (such as the Six-Minute Walk Test and cardiopulmonary exercise testing) * Have blood pressure and heart rate measured * Complete questionnaires about symptoms, physical function, sleep quality, and quality of life
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 11 Mar 2026
- Start date
- 25 Dec 2023
- Primary completion date
- 24 Jun 2024
- Lead sponsor
- National Defense Medical Center, Taiwan
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT07492953
What you commit to
- Study type: Interventional
- Participants enrolled: 10
- From 25 Dec 2023 to the primary completion date, 24 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Aortic aneurysm requiring surgical repair
Other illness
- Severe peripheral arterial disease or limb ischemia
- Active deep vein thrombosis
- Other serious cardiovascular conditions contraindicating EECP
- Severe neurocognitive impairment precluding consent or cooperation.
Other
- Aortic valve regurgitation,
- Pregnancy
- Unable to ambulate
Who the study is looking for
- Age ≥ 20 years
- Eligible for follow-up ≥3 months
- A confirmed history of COVID-19 (via PCR or antigen test)
- Post-COVID-19 with persistent symptoms ( fatigue, exercise intolerance, dyspnea on exertion, and/or cognitive difficulties) for ≥3 months
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Natioanl Denfense Medical University Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.