NCT07493434Enrolling by invitation
Evaluation of Pain Thresholds in Migraine Patients After Inhalation of Essential Oils: a Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 25 Mar 2026
Brief summary (registry, in English)
This study will test whether inhaling essential oils can change how sensitive people with migraine are to pressure pain. Participants will be allocated to inhale lavender, peppermint, a combination of both, or a control solution (distilled water with coconut oil). Each group will have 50 participants. The inhalation will last 15 minutes and will happen only once. Before and after the inhalation, we will measure how much pressure on certain areas of the head.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 14 Mar 2026
- Start date
- 13 Mar 2025
- Primary completion date
- Mar 2027
- Lead sponsor
- University of Sao Paulo
- Diseases
- Migraine
- NCT number
- NCT07493434
What you commit to
- Study type: Interventional
- Planned participants: 200
- From 13 Mar 2025 to the primary completion date, Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe acute circulatory disorders
- Diabetes melitus
- Uncontrolled arterial hypertension
- Known allergy or hypersensitivity to essential oils or their components
Other
- Fribromyagia
- Anosmia or hyposmia
- Pregnancy or breastfeeding
Who the study is looking for
- Adults aged 18-65 years
- Diagnosis of episodic or chronic migraine according to the Internactional Classification of Headache Disorders (ICDH-3)
- History of migraine for at least 1 year
- Ability to understand and provide informed consent
- Participants currently using or not using migraine preventive medication
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Intitute of Psychiatry- Hospital das Clínicas, University of São Paulo Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.