NCT07493707Active, not recruiting
Effect of an Intervention With Apple Cider Vinegar on Glycemic Variability and Lipid Profile in Patients With Type 2 Diabetes Mellitus
Source: ClinicalTrials.gov · Last updated 10 Aug 2026
Brief summary (registry, in English)
The objective of this open-label, randomized, crossover clinical trial is to determine the effect of consuming 15 ml of organic apple cider vinegar on glycemic variability, measured by the coefficient of variation of glucose, in adults with type 2 diabetes mellitus. The main question this study seeks to answer is: What is the effect of consuming 15 ml of organic apple cider vinegar every 12 hours for a period of 2 weeks on the coefficient of variation of glucose in adults aged 18 to 60 years with type 2 diabetes mellitus, compared to consuming 250 ml of natural water? The researchers will compare the consumption of organic apple cider vinegar with natural water to evaluate whether organic apple cider vinegar has an impact on glycemic variability. Participants, in a crossover design, will use a continuous glucose monitor throughout the study. In one phase, they will consume 15 ml of apple cider vinegar before breakfast and before dinner for a period of 14 days, and in the other phase, they will consume 250 ml of natural water for the same period, with a washout period between both phases. Glucose data obtained through the continuous glucose monitor will be used to calculate the coefficient of variation as the primary measure of glycemic variability.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 38 (estimated)
- First submitted
- 16 Mar 2026
- Start date
- 6 May 2024
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Diseases
- Type 2 diabetes
- NCT number
- NCT07493707
What you commit to
- Study type: Interventional
- Planned participants: 38
- From 6 May 2024 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of systemic steroids at supraphysiological doses
Other illness
- Other types of diabetes
- Allergy to apple cider vinegar
- Gastroesophageal reflux disease
- Peptic ulcer disease
Lab values
- Chronic kidney disease (eGFR \< 60 ml/min)
Other
- Documented gastroparesis
- Pregnancy or lactation
- Use of rapid-acting prandial insulin or analogs
Who the study is looking for
- Men and women
- Diagnosis of type 2 diabetes mellitus
- Age between 18 and 60 years
- Glycated hemoglobin (HbA1c) ≤ 8%
- Participant's ability to attend medical appointments, answer questionnaires, and undergo laboratory tests.
- Participant's ability to wear a Freestyle® device.
- Participant's acceptance and signature of informed consent.
- Acceptance of the intervention (consumption of 30 ml of apple cider vinegar) and avoidance of vinegar-based dressings for the entire duration of the intervention.
- Consent to participate in the study.
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Coordinator of this site? Confirm its status | Mexico City | Mexico | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.