Fact CheckerSign in

NCT07494006Enrolling by invitation

Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?

Association Between Spontaneous Breathing Mode and Hypoxemia During One-Lung Ventilation Under General Anesthesia

Source: ClinicalTrials.gov · Last updated 27 Mar 2026

Brief summary (registry, in English)

Patients undergoing thoracic surgery with one-lung ventilation (OLV) are prone to hypoxemia, which is primarily attributable to pulmonary ventilation-perfusion (V/Q) mismatch. This study will preoperatively assess the distribution of pulmonary ventilation under spontaneous breathing and intraoperatively record the lowest peripheral oxygen saturation (SpO₂) during OLV. The aim is to investigate the correlation between these two parameters. The findings are expected to facilitate the prediction of hypoxemia in thoracic surgical patients undergoing OLV.

Status (registry)
Enrolling by invitation
Study type
Observational
Enrollment
44 (estimated)
First submitted
8 Dec 2025
Start date
15 Jul 2025
Primary completion date
30 Jun 2026
Lead sponsor
Peking University People's Hospital
Diseases
Lung cancer
NCT number
NCT07494006

What you commit to

  • Study type: Observational
  • Planned participants: 44
  • From 15 Jul 2025 to the primary completion date, 30 Jun 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • • Inability to use the EIT belt preoperatively
    • Failure to implement one-lung ventilation during surgery

Who the study is looking for

  • Age ≥ 18 years
    • BMI \> 18.5 and \< 30
    • Informed consent obtained

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Peking University People's Hospital
Coordinator of this site? Confirm its status
BeijingChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.