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NCT07495657Not yet recruiting

Pre-Post Multimodal Assessment Of Severe Psoriasis Vulgaris Using Clinical, Dermoscopic And QoL Measures

Multimodal Evaluation of Severe Psoriasis Vulgaris Before and After Treatment Using Clinical, Dermoscopic, Psoriasis Disability Index, and Quality of Life Parameters

Source: ClinicalTrials.gov · Last updated 27 Mar 2026

Brief summary (registry, in English)

The goal of this observational study is to learn about the comprehensive changes in severe plaque psoriasis (Psoriasis Vulgaris) in adult participants undergoing standard treatment. The main questions it aims to answer are: How clinical signs of psoriasis, such as redness, scaling, and thickness, change after treatment? How specific skin features, visualized under dermoscopy, change after treatment? How participants' perceptions of psoriasis-related disability and overall quality of life improve after treatment? Participants will undergo standard medical treatment for severe psoriasis. Participants will be evaluated at the beginning of the study and again after treatment using clinical skin examinations, dermoscopic imaging, and validated questionnaires (Psoriasis Disability Index and quality of life parameters).

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
45 (estimated)
First submitted
19 Mar 2026
Start date
1 May 2026
Primary completion date
1 May 2027
Lead sponsor
Assiut University
Diseases
Psoriasis
NCT number
NCT07495657

What you commit to

  • Study type: Observational
  • Planned participants: 45
  • From 1 May 2026 to the primary completion date, 1 May 2027
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • • Non cooperative patients .
    • Pregnant or breastfeeding women

Who the study is looking for

  • Patients ≥ 6 years of age
    • Newly diagnosed patients with plaque psoriasis with affected BSA \>10%
    • Indicated for a new systemic therapy (e.g., oral agent, biologics).
    • Willing and able to provide informed consent for all procedures .
    • At least one eligible, representative target plaque for serial dermoscopic imaging .
    • Stop previous systemic therapy at least 2-3 months

Age in the registry: 6 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.