NCT07496775Recruiting
Cardiovascular Acoustics for Early Disease Detection
ACOUTECT: Cardiovascular Acoustics for Early Disease Detection
Source: ClinicalTrials.gov · Last updated 28 Oct 2026
Brief summary (registry, in English)
There are many types of heart disease. Two of the most common causes are narrowings within the blood vessels that supply the heart (known as coronary artery disease), or valves within the heart becoming narrowed (stenosed) or leaky (regurgitation), known as heart valve disease. There are two main types of imaging used to test for these conditions. Coronary artery disease can be diagnosed by taking X-ray pictures of a dye when injected into the blood vessels. In some cases the dye is injected into the veins and a CT scanner is used (CT coronary angiography), in others the dye is injected via a tube placed in the artery (invasive coronary angiography). Valvular heart disease is normally diagnosed using an echocardiogram (ultrasound of the heart). In this study the investigators are looking for subtle changes in the sounds that come from the heart, which may allow heart disease to be detected earlier. The investigators are using a novel device, similar to a digital stethoscope, that has excellent sensitivity for heart sounds. Ultimately this may be used in community settings including GP surgeries, in this study the investigators are collecting sounds from patients undergoing routine scans as part of their workup for heart disease.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 23 Mar 2026
- Start date
- 10 Jun 2026
- Primary completion date
- Dec 2027
- Lead sponsor
- Cambridge University Hospitals NHS Foundation Trust
- Diseases
- Coronary artery disease
- NCT number
- NCT07496775
What you commit to
- Study type: Observational
- Planned participants: 500
- From 10 Jun 2026 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous valve intervention
Other illness
- Heart failure symptoms with NYHA 4
- Uncontrolled symptomatic arrhythmia
Other
- Haemodynamic instability
- STEMI or high risk NSTEMI
- Anginal symptoms at rest
- Cardiovascular related admission or event occurring between imaging studies
- Acute pulmonary embolism
- Acute aortic dissection
- Suspected endocarditis
Who the study is looking for
- Participants aged ≥18 years
- Able to provide written, informed consent
- Has undergone angiography in the previous 6 months and scheduled to undergo transthoracic echocardiography, or has undergone transthoracic echocardiography in the previous 6 months and scheduled to undergo angiography, or is scheduled to undergo transthoracic echocardiography and angiography within 6 months.
- Angiography and echocardiography performed within Cambridge University Hospitals NHS Foundation Trust.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cambridge University NHS Foundation Trust Coordinator of this site? Confirm its status | Cambridge | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.