NCT07497867Recruiting
Long-term Prospective Study of Korean CADASIL Patients
Long-term Prognosis of Korean Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy(CADASIL) Patients: A Multicenter Prospective Study
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
K-CADASIL is a 10-year prospective study of 500 Korean patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic brain disease that causes stroke and dementia. The investigators will track symptoms, brain scans, memory tests, and gene information to understand disease progression in Koreans and identify better treatments. Participants will visit clinics regularly for check-ups and blood tests. This study aims to help improve care for CADASIL patients and families worldwide.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 23 Mar 2026
- Start date
- 10 Jul 2023
- Primary completion date
- 31 Dec 2035
- Lead sponsor
- Jeju National University Hospital
- Diseases
- Stroke
- NCT number
- NCT07497867
What you commit to
- Study type: Observational
- Planned participants: 500
- From 10 Jul 2023 to the primary completion date, 31 Dec 2035
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindication to MRI (claustrophobia, metal implants, pacemaker)
- Acute ischemic or hemorrhagic stroke within 180 days prior to enrollment
Who the study is looking for
- Age ≥ 19 years
- CADASIL suspected or confirmed by genetic testing (NOTCH3 mutation)
- Able to provide written informed consent (participant or legally authorized representative)
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Jeju National University Hospital Coordinator of this site? Confirm its status | Jeju City | South Korea | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.