NCT07499830Completed
Performance of an OCR-Prompt-LLM Integrated Workflow for Extracting Multi-dimensional Clinical Data in Ischemic Heart Disease
Source: ClinicalTrials.gov · Last updated 30 Mar 2026
Brief summary (registry, in English)
This research aims to evaluate a comprehensive AI-driven workflow for both clinical data extraction and diagnostic classification in coronary artery disease (CAD). Leveraging OCR and Large Language Models (LLMs), the system is designed to extract ten key clinical parameters (such as LVEF and lab results) and provide diagnostic subtypes (UA, STEMI, NSTEMI, CCS) directly from unstructured inpatient records. A man-machine comparative trial will be conducted using a test set of 308 patients, where the performance of the LLM-based workflow will be benchmarked against the average diagnostic accuracy and processing time of seven clinical physicians. The findings will provide evidence for the feasibility of using LLMs to enhance clinical data structuring and diagnostic efficiency in cardiology.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 308 (actual)
- First submitted
- 24 Mar 2026
- Start date
- 23 Feb 2026
- Primary completion date
- 1 Mar 2026
- Lead sponsor
- China National Center for Cardiovascular Diseases
- Diseases
- Coronary artery disease
- NCT number
- NCT07499830
What you commit to
- Study type: Observational
- Participants enrolled: 308
- From 23 Feb 2026 to the primary completion date, 1 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Clinical records with severe data fragmentation or missing more than 50% of the key clinical indicators.
- Handwritten medical records or low-quality scans that are illegible for Optical Character Recognition (OCR) processing.
- Duplicate records or records with conflicting "Gold Standard" labels that cannot be reconciled by the expert committee.
Who the study is looking for
- Patients aged 18 years and older.
- Clinical records of patients who were previously enrolled in the AIM-CHD (for the pilot/prompt optimization set) or SMART-CHD (for the internal validation cohort) studies.
- Patients diagnosed with, or suspected of having, coronary artery disease (CAD), including subtypes: Unstable Angina (UA), STEMI, NSTEMI, and Chronic Coronary Syndrome (CCS).
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fuwai Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.