NCT07500376Recruiting
Multimodal Nutritional and Sarcopenia Assessment for Risk Stratification in Lung Cancer Surgery
Prognostic Value of Multimodal Nutritional Status and Sarcopenia Assessment for Postoperative Risk Stratification in Patients Undergoing Lung Cancer Surgery: A Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 24 Jul 2026
Brief summary (registry, in English)
This prospective observational cohort study aims to evaluate the prognostic value of multimodal nutritional status and sarcopenia assessment in patients undergoing lung cancer surgery. Postoperative complications, mortality, and prolonged hospital stay remain major clinical concerns in thoracic surgery. Although malnutrition and sarcopenia are recognized as important determinants of surgical outcomes, their combined and multidimensional evaluation has not been sufficiently studied. Adult patients undergoing anatomical lung resection for primary lung cancer will be included. Nutritional status will be assessed using serum biomarkers, inflammatory indices, and validated clinical nutritional scores. Sarcopenia will be evaluated using computed tomography-based muscle mass and density measurements, as well as ultrasonographic muscle thickness. These parameters will be analyzed in relation to postoperative complications, intensive care unit (ICU) requirement, length of hospital stay, and mortality. Multivariable analyses will be performed to identify independent predictors, and a combined risk stratification model will be developed. This study aims to improve preoperative risk assessment and to support personalized perioperative management strategies, including identification of patients who may benefit from targeted nutritional optimization and prehabilitation.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 142 (estimated)
- First submitted
- 24 Mar 2026
- Start date
- 15 Mar 2026
- Primary completion date
- 15 Feb 2027
- Lead sponsor
- Ondokuz Mayıs University
- Diseases
- Lung cancer
- NCT number
- NCT07500376
What you commit to
- Study type: Observational
- Planned participants: 142
- From 15 Mar 2026 to the primary completion date, 15 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Receipt of neoadjuvant chemotherapy, immunotherapy, or radiotherapy
- Emergency surgery
- Combined resection of another organ during the same procedure
- Significant thoracic deformity or prior conditions interfering with muscle measurements
Other illness
- Immunosuppressive therapy or presence of advanced/metastatic disease
Other
- Pneumonectomy
- Inadequate or non-evaluable imaging or measurement data
- Refusal or inability to provide informed consent
Who the study is looking for
- Age ≥18 years
- Patients undergoing anatomical lung resection (lobectomy or segmentectomy) for primary lung cancer
- Availability of preoperative thoracic computed tomography (CT) within 30 days before surgery
- Completion of preoperative nutritional assessment and ultrasonographic muscle measurements
- Ability to provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ondokuz Mayis University Faculty of Medicine, Department of Thoracic Surgery Coordinator of this site? Confirm its status | Samsun | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.