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NCT07501780Recruiting

Real-world Evaluation of the Implementation of LC-OCT in Daily Clinical Practice

Real-world Evaluation of the Implementation of LC-OCT in Daily Clinical Practice: a Retrospective Observational Study

Source: ClinicalTrials.gov · Last updated 19 Oct 2026

Brief summary (registry, in English)

Basal cell carcinoma (BCC) is the most common skin cancer in the Netherlands, with incidence rates continuing to rise. The current diagnostic standard combines clinical evaluation and dermoscopy, while biopsy followed by histopathological examination remains the gold standard when uncertainty about the diagnosis persists. However, biopsy is invasive, time-consuming, and costly. Line-field confocal optical coherence tomography (LC-OCT) is a non-invasive imaging technique that has emerged as a promising alternative to biopsy for BCC suspected lesions. This retrospective study aims to evaluate the real-world clinical performance of LC-OCT in routine dermatological practice, where it has been integrated into the diagnostic work-up for BCC-suspect lesions.

Status (registry)
Recruiting
Study type
Observational
Enrollment
297 (estimated)
First submitted
16 Mar 2026
Start date
15 Jun 2026
Primary completion date
15 Aug 2027
Lead sponsor
Maastricht University Medical Center
Diseases
Melanoma
NCT number
NCT07501780

What you commit to

  • Study type: Observational
  • Planned participants: 297
  • From 15 Jun 2026 to the primary completion date, 15 Aug 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Patients \<18 years of age

Other

  • Cases without histopathological confirmation or available follow-up data

Who the study is looking for

  • Patients aged ≥18 years
  • LC-OCT performed as part of diagnostic evaluation between January 2025 and June 2025 at Mohs clinics in the Netherlands
  • Histopathological results (biopsy or excision) and/or 6-12 month clinical follow-up data available

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Maastricht University Medical Center
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MaastrichtNetherlandsRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.