NCT07503847Enrolling by invitation
Shared Decision-Making for Colorectal Cancer Screening in High-Risk First-Degree Relatives Aged 40-49
A Randomized Controlled Trial on Shared Decision-Making for Colorectal Cancer Screening Among High-Risk First-Degree Relatives Aged 40-49
Source: ClinicalTrials.gov · Last updated 31 Mar 2026
Brief summary (registry, in English)
The primary objective of this study was to evaluate the impact of a constructed shared decision (SDM) intervention (offering an option between colonoscopy and immunochemical collapsible occult blood testing (fecal immunochemical test; FIT)) on improving the incidence of high colonoscopy stromal in patients aged 40-49 years with a close relative suffering from colorectal cancer, compared to standard care (direct referral for colonoscopy).
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 2286 (estimated)
- First submitted
- 10 Mar 2026
- Start date
- 1 Sept 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- National Taiwan University Hospital
- Diseases
- Colorectal cancer
- NCT number
- NCT07503847
What you commit to
- Study type: Interventional
- Planned participants: 2286
- From 1 Sept 2025 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- A personal history of colorectal cancer or inflammatory bowel disease (Crohn's disease or ulcerative colitis).
- Presence of warning signs of colorectal cancer requiring diagnostic evaluation rather than screening (e.g., unexplained rectal bleeding, significant involuntary weight loss, persistent changes in bowel habits).
Other
- Presence of comorbidities that may contraindicate colonoscopy.
- Having undergone colonoscopy within the past three years.
- Inability to read, understand, and provide written informed consent.
Who the study is looking for
- Age 40 to 49 years at the time of recruitment.
- At least one immediate family member (biological parent, sibling, or child) has been pathologically diagnosed with colorectal cancer.
- Able to read, understand, and provide prior consent.
- Willing to be randomly assigned to any research group and complete all research procedures.
Age in the registry: 40 years to 49 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Taiwan University Hospital Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.