NCT07504172Completed
Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity
Real-world Effectiveness and Dosing Patterns of Tirzepatide: A Multicentre Retrospective Observational Study in the Netherlands
Source: ClinicalTrials.gov · Last updated 28 Oct 2026
Brief summary (registry, in English)
Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 915 (actual)
- First submitted
- 20 Mar 2026
- Start date
- 1 Apr 2026
- Primary completion date
- 11 Jun 2026
- Lead sponsor
- Radboud University Medical Center
- Diseases
- Obesity
- NCT number
- NCT07504172
What you commit to
- Study type: Observational
- Participants enrolled: 915
- From 1 Apr 2026 to the primary completion date, 11 Jun 2026
- 10 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previously treated for obesity (with pharmacotherapy, endoscopic treatment or metabolic-bariatric surgery)
Other illness
- Patients with diabetes
Other
- Pregnant women or pregnancy during treatment
Who the study is looking for
- Adults (age ≥18 years old)
- A BMI of ≥ 30 kg/m2 or a BMI ≥ 27 kg/m2 with at least one obesity complication (e.g., hypertension, dyslipidaemia)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| NOK clinics Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Arnhem | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Beverwijk | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Gouda | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Heerlen | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Hoogeveen | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Nieuwegein | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Terneuzen | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | The Hague | Netherlands | Unknown status |
| NOK clinics Coordinator of this site? Confirm its status | Venlo | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.