Fact CheckerSign in

NCT07504172Completed

Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

Real-world Effectiveness and Dosing Patterns of Tirzepatide: A Multicentre Retrospective Observational Study in the Netherlands

Source: ClinicalTrials.gov · Last updated 28 Oct 2026

Brief summary (registry, in English)

Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).

Status (registry)
Completed
Study type
Observational
Enrollment
915 (actual)
First submitted
20 Mar 2026
Start date
1 Apr 2026
Primary completion date
11 Jun 2026
Lead sponsor
Radboud University Medical Center
Diseases
Obesity
NCT number
NCT07504172

What you commit to

  • Study type: Observational
  • Participants enrolled: 915
  • From 1 Apr 2026 to the primary completion date, 11 Jun 2026
  • 10 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previously treated for obesity (with pharmacotherapy, endoscopic treatment or metabolic-bariatric surgery)

Other illness

  • Patients with diabetes

Other

  • Pregnant women or pregnancy during treatment

Who the study is looking for

  • Adults (age ≥18 years old)
  • A BMI of ≥ 30 kg/m2 or a BMI ≥ 27 kg/m2 with at least one obesity complication (e.g., hypertension, dyslipidaemia)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (10)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
NOK clinics
Coordinator of this site? Confirm its status
AmsterdamNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
ArnhemNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
BeverwijkNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
GoudaNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
HeerlenNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
HoogeveenNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
NieuwegeinNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
TerneuzenNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
The HagueNetherlandsUnknown status
NOK clinics
Coordinator of this site? Confirm its status
VenloNetherlandsUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.