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NCT07506902Recruiting

A Study of Adaptive Radiotherapy of Head-neck Cancer Using Daily Replanning and Optimization of the Treatment Plan.

DART-HN - Daily Adaptive Radiotherapy of Head-neck Cancer.

Source: ClinicalTrials.gov · Last updated 2 Apr 2026

Brief summary (registry, in English)

Radiotherapy of head-neck cancer is associated with significant side effects. Using daily online adaptive radiotherapy to account for the changing anatomy, radiation to organs at risk can be lowered. We will investigate whether this is feasible and associated with a reduction in the risk of toxicity.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
40 (estimated)
First submitted
26 Mar 2026
Start date
21 Nov 2023
Primary completion date
31 Dec 2027
Lead sponsor
Copenhagen University Hospital, Rigshospitalet
NCT number
NCT07506902

What you commit to

  • Study type: Interventional
  • Planned participants: 40
  • From 21 Nov 2023 to the primary completion date, 31 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Inability to attend full course of radiotherapy or follow-up visits in the outpatient clinic Distant metastasis Previous radiotherapy of the head and neck Previous surgery for the primary cancer with curative intent

Other illness

  • Patient with cancers of the glottic larynx (stage I/II), skull base, sino-nasal area and unknown primary tumor.

Other

  • \-

Who the study is looking for

  • Patients with histologically proven squamous cell carcinoma of the pharynx or larynx planned for primary radiotherapy with curative intent No current or earlier malignancies, which may influence treatment, evaluation or outcome of the head-neck cancer Informed consent as required by law The patient cannot participate in conflicting protocols Stage I-IV (excluding T1-T2N0 carcinoma of the glottic larynx) ECOG/WHO performance status 0-2

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Rigshospitalet
Coordinator of this site? Confirm its status
CopenhagenDenmarkRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.