NCT07507084Recruiting
The Effect of Internal- or External-Focused Exercise Training, Administered in Conjunction With a Cognitive Task, on Walking, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 1 Jul 2026
Brief summary (registry, in English)
This interventional clinical trial aims to investigate the effects of internal and external focus-based exercise training combined with cognitive dual-task training in individuals diagnosed with multiple sclerosis. The primary objective is to determine whether these exercise approaches improve gait, balance, and cognitive functions. The main research questions are: Does dual-task training combined with internal focus-based exercises improve gait, balance, and cognitive performance? Does dual-task training combined with external focus-based exercises lead to greater improvements compared to internal focus strategies? Participants will be divided into two groups, and the researchers will compare the effects of internal focus-based and external focus-based dual-task exercise training on functional outcomes. Participants will: Perform structured exercise sessions under the supervision of a physiotherapist Engage in dual-task activities by combining motor exercises with simple cognitive tasks (e.g., backward counting, word generation) Participate in an 8-week training program, with sessions held twice a week lasting approximately 45-60 minutes Undergo assessments of gait, balance, and cognitive function before and after the intervention This study does not involve invasive procedures or biological sample collection. The findings are expected to contribute to the development of more effective dual-task rehabilitation strategies for individuals with multiple sclerosis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 27 Mar 2026
- Start date
- 15 Mar 2026
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Kutahya Health Sciences University
- Diseases
- Multiple sclerosis
- NCT number
- NCT07507084
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 15 Mar 2026 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of any other neurological disease besides Multiple Sclerosis
- Any musculoskeletal condition that may affect walking or balance
- History of uncontrolled cardiorespiratory conditions within the last 3 months (e.g., hypertension, arrhythmia, tachycardia, or acute cardiopulmonary events)
- Severe visual or hearing impairment
Other
- MS relapse within the last 30 days
Who the study is looking for
- Diagnosis of Multiple Sclerosis according to the revised McDonald criteria
- Aged between 20 and 60 years
- Ability to understand and follow simple instructions
- Ability to stand and walk independently or with an assistive device
- Ability to speak and understand Turkish
- Score of ≥21 on the Montreal Cognitive Assessment (MoCA)
- Willingness to participate in the study
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kütahya Sağlık Bilimleri Üniversitesi, Sağlıklı Yaşam Fizyoterapi ve Rehabilitasyon Merkezi Coordinator of this site? Confirm its status | Kütahya | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.