NCT07507929Not yet recruiting
Probiotic for Weight Management in Overweight and Obese Adults
Effectiveness and Safety of Inactivated Akkermansia Muciniphila Akk11 (34B) on Weight and Energy Metabolism in Overweight and Obese Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
Source: ClinicalTrials.gov · Last updated 2 Apr 2026
Brief summary (registry, in English)
To evaluate the impact of pasteurized Akkermansia muciniphila Akk11 capsules versus placebo on body composition (including body weight, BMI, body fat percentage, waist-to-hip ratio, wrist circumference, visceral fat area, and basal metabolic rate) and serum lipid parameters (TC, LDL-C, HDL-C, and TG) in overweight and obese adults.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 76 (estimated)
- First submitted
- 27 Mar 2026
- Start date
- Mar 2026
- Primary completion date
- Dec 2026
- Lead sponsor
- Wecare Probiotics Co., Ltd.
- Diseases
- Obesity
- NCT number
- NCT07507929
What you commit to
- Study type: Interventional
- Planned participants: 76
- From Mar 2026 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent use of products with similar functions to the investigational product that may interfere with study outcomes;
- Use of antibiotics within 3 months prior to screening;
- Inability to comply with the study protocol, including failure to take the investigational product as required or attend scheduled follow-up visits;
Other illness
- History of psychiatric or neurological disorders, celiac disease, lactose intolerance, or known allergies;
- Diagnosis of irritable bowel syndrome (IBS), ulcerative colitis, liver cirrhosis, or diabetes mellitus;
- Any other condition that, in the opinion of the investigator, would make the participant unsuitable for the study.
Other
- Pregnant or breastfeeding women, or those planning to become pregnant during the study period;
- Smoking more than 10 cigarettes per day;
Who the study is looking for
- Body mass index (BMI) ≥ 24 kg/m²;
- Able and willing to provide written informed consent;
- Willing to comply with the study protocol and required restrictions, including adherence to a low-carbohydrate, energy-restricted diet;
- No intention to conceive from 14 days prior to screening until 6 months after study completion, and agreement to use effective contraception during this period
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The School of Food and Bioengineering, Henan University of Science and Technolog Coordinator of this site? Confirm its status | Luoyang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.