NCT07509606Recruiting
Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD)
Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Lung Function, Respiratory Function, Upper Extremity Strength and Flexibility, Cardiac Automatic Function and Quality of Life in Healthy and Moderate and Severe Chronic Obstructive Pulmonary Disease (COPD)
Source: ClinicalTrials.gov · Last updated 3 Apr 2026
Brief summary (registry, in English)
Chronic obstructive pulmonary disease (COPD) is an irreversible disorder characterized by persistent airflow limitation and increased lung compliance. It leads to dyspnea, skeletal muscle dysfunction, impaired functional capacity, and reduced quality of life. Physical inactivity is considered a major contributor to symptom deterioration, the development of a vicious cycle, and ultimately increased mortality. According to the American College of Sports Medicine (ACSM), the American Thoracic Society (ATS), and the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), pulmonary rehabilitation should include aerobic and resistance exercise for at least 20 minutes per session, performed three to five times per week for a minimum of 12 weeks. Exercise intensity should be progressively increased to exceed 60% of peak oxygen uptake (VO₂peak), and patients are encouraged to maintain long-term exercise habits. However, there is still no consensus regarding the optimal initial intensity, progression strategy, and exercise duration. Previous studies have demonstrated that whole-body vibration (WBV) can improve lower extremity muscle strength, functional capacity, and quality of life in patients with COPD. However, its effects on lung function and the optimal training dose remain unclear. In addition, COPD also affects respiratory muscles, upper extremity strength and flexibility, as well as cardiac autonomic function. Therefore, the aim of this study is to investigate the effects of different WBV frequencies on lung function, respiratory muscle function, upper extremity strength and flexibility, and cardiac autonomic function, in order to determine the optimal training dose.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 102 (estimated)
- First submitted
- 29 Mar 2026
- Start date
- 7 Apr 2025
- Primary completion date
- 8 May 2025
- Lead sponsor
- National Cheng Kung University
- Diseases
- COPD
- NCT number
- NCT07509606
What you commit to
- Study type: Interventional
- Planned participants: 102
- From 7 Apr 2025 to the primary completion date, 8 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent wounds due to injury or surgery.
- Hip or knee implants.
- Hip or knee implants.
- Recent wounds due to injury or surgery.
Other illness
- Acute thrombosis.
- Severe cardiovascular disease.
- Presence of a cardiac pacemaker.
- Severe diabetes mellitus.
- Epilepsy.
- Recent infection.
- Organ failure.
- Presence of musculoskeletal, respiratory, neurological, cardiovascular conditions, or any form of acute or chronic pain.
- Severe respiratory diseases (e.g., bronchiectasis, pulmonary fibrosis, asthma, or tuberculosis).
- Severe joint disease or history of lower extremity surgery.
- History of vitreous hemorrhage.
- Acute thrombosis.
- Presence of a cardiac pacemaker.
- Severe diabetes mellitus.
- Epilepsy.
- Recent infection.
- Organ failure.
Other
- Pregnancy.
- Acute hernia, intervertebral disc degeneration, or spondylolysis.
- Severe migraine.
- Tumor.
- Recently implanted intrauterine device, metal pins, or metal plates.
- Kidney stones.
- Participation in other research studies concurrently.
- Regular exercise habits (engaging in moderate-intensity exercise ≥3 times per week).
- COPD
- Current smokers.
- Dependence on supplemental oxygen.
- Severe alcohol abuse (\>80 g/day).
- Severe malnutrition (BMI \< 19 kg/m²).
- Pregnancy.
- Acute hernia, intervertebral disc degeneration, or spondylolysis.
- Severe migraine.
- Tumor.
- Recently implanted intrauterine device, metal pins, or metal plates.
- Kidney stones.
- Altered consciousness or inability to comply with assessments.
- Participation in other research studies concurrently
Who the study is looking for
- No prior experience with whole-body vibration therapy or exposure to vibration-related occupations or sports.
- Aged between 18 and 65 years.
- Clinically diagnosed with chronic obstructive pulmonary disease (COPD) and classified as Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage II, III, or IV.
- No history of hospitalization within the past two months.
- No participation in any rehabilitation program within the past two months.
- Able to comply with the exercise training program.
- Aged 18 years or older.
Criteria the registry did not label
- Healthy individuals
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Cheng Kung University Hospital Coordinator of this site? Confirm its status | Tainan | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.