NCT07511283Recruiting
Calciphylaxis in Patients With Chronic Kidney Disease - A Study of the Danish Calciphylaxis Research Initiative (DanCaRI)
Source: ClinicalTrials.gov · Last updated 6 Apr 2026
Brief summary (registry, in English)
Calciphylaxis is a rare yet life-threatening condition involving pronounced calcification in small blood vessels of the skin. Knowledge about its underlying mechanisms and contributing risk factors remains limited. Chronic kidney disease is one of the strongest disease predictors. No evidence based effective therapy is currently available. Research on the topic is mainly hindered by the condition's rarity. The study Calciphylaxis in patients with chronic kidney disease - A study of the Danish Calciphylaxis Research Initiative (DanCaRI) is set up to facilitate the systematic retrospective and prospective comparison of patients with chronic kidney disease and calciphylaxis to matched patients with chronic kidney disease who did not develop calciphylaxis thereby providing new knowledge that can support prevention, early detection, and new treatment approaches.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 860 (estimated)
- First submitted
- 30 Mar 2026
- Start date
- 1 Apr 2026
- Primary completion date
- 30 Jun 2040
- Lead sponsor
- Odense University Hospital
- Diseases
- Chronic kidney disease
- NCT number
- NCT07511283
What you commit to
- Study type: Observational
- Planned participants: 860
- From 1 Apr 2026 to the primary completion date, 30 Jun 2040
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Lab values
- Healthy controls Up to 60 years of age: eGFR below 60 ml/min/1.72m2.
- \- Over 60 years of age: eGFR below the 95% confidence interval for eGFR adjusted for age (Danish Society of Nephrology references ranges)
Other
- Cases
- \- the calciphylaxis diagnosis becomes excluded
- Controls - Being diagnosed with calciphylaxis
Who the study is looking for
- Cases
- Age ≥18 years.
- CKD.
- Suspicion of calciphylaxis or newly diagnosed calciphylaxis episode. The suspicion or diagnosis of calciphylaxis is a mutual decision of the involved medical specialties (nephrologist, dermatologist, pathologist, other).
- Ability to give informed consent.
- Ability to participate in a clinical study as assessed by the local investigator.
- Provides written informed consent.
- Controls
- Age ≥18 years.
- CKD
- Ability to give informed consent.
- Ability to participate in a clinical study as assessed by the local investigator.
- Provides written informed consent.
- Healthy reference group
- Age ≥18 years.
- Self-assessed as healthy, confirmed by local investigators at inclusion
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Odense University Hospital Coordinator of this site? Confirm its status | Odense | Denmark | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.