NCT07513441RecruitingPhase 1
A Trial of Lu AF28996 in Participants With Parkinson's Disease (PD)
Interventional, Open-label, Trial Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Lu AF28996 in Chinese Men and Women With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 10 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to investigate the safety of Lu AF28996, how well it is tolerated and what the body does to the drug in participants with Parkinson's disease.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 31 Mar 2026
- Start date
- 26 May 2026
- Primary completion date
- 31 May 2027
- Lead sponsor
- H. Lundbeck A/S
- Diseases
- Parkinson disease
- NCT number
- NCT07513441
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 10
- From 26 May 2026 to the primary completion date, 31 May 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- The participant has received oral or transdermal dopamine agonist treatment ≤4 weeks prior to screening.
- The participant has received Traditional Chinese Medicine treatment ≤4 weeks prior to screening.
- Note: Other protocol-defined inclusion and exclusion criteria may apply.
Other illness
- The participant has undergone a neurosurgical intervention for Parkinson's disease (such as pallidotomy, thalamotomy, foetal or stem cell transplantation or deep brain stimulation).
- The participant has any other disorder for which the treatment takes priority over treatment of Parkinson's disease or is likely to interfere with trial treatment or impair treatment compliance.
Who the study is looking for
- The participant is Chinese, defined as having four Chinese grandparents being born in China.
- The participant is diagnosed with idiopathic Parkinson's disease (consistent with the United Kingdom PD Society Brain Bank Criteria for the Diagnosis of PD).
- The participant's Modified Hoehn and Yahr score is ≥2 and ≤4 (in OFF) and ≤3 in the ON state.
- The participant experiences well recognizable and predictable motor fluctuations in the awake time including predictable morning OFF episodes causing clinically significant disability during the last 3 months prior to screening, as evaluated by the investigator.
Age in the registry: 35 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beijing TiantanHospital, CapitalMedical University Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
| Xuanwu Hospital, Capital Medical University Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
| West China Hospital,Sichuan University Coordinator of this site? Confirm its status | Chengdu | China | Recruiting |
| Fudan University - Huashan Hospital - Institute of Urology Coordinator of this site? Confirm its status | Shanghai Shi | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.