NCT07513610Completed
The Effects of Quinoa and Buckwheat on Weight Management and Gut Microbiome
The Effects of Dietary Quinoa and Buckwheat Consumption on Weight Management and Gut Microbiome
Source: ClinicalTrials.gov · Last updated 7 Apr 2026
Brief summary (registry, in English)
This study aims to compare the effects of quinoa, buckwheat, rice, and bulgur consumption on dietary intake, anthropometric measurements, glycemic response, lipid profile, inflammatory markers, blood pressure, and intestinal microbiome in people with overweight and obesity. The primary hypotheses of the studies were given as follows: Hypothesis 1: H1: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet provides weight loss. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not provide body weight loss. Hypothesis 2: H2: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet affects glycemic response. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not affect glycemic response. Hypothesis 3: H3: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet affects the blood lipid profile. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not affect the blood lipid profile. Hypothesis 4: H4: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet changes the composition of the gut microbiome. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not change the composition of the gut microbiome. Hypothesis 5: H5: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet increases alpha diversity in the intestinal microbiome. HO: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not increase alpha diversity in the intestinal microbiome. Hypothesis 6: H6: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet increases beta diversity in the intestinal microbiome. HO: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not increase beta diversity in the intestinal microbiome.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 148 (actual)
- First submitted
- 14 Mar 2026
- Start date
- 24 Jan 2024
- Primary completion date
- 17 Jan 2025
- Lead sponsor
- Hacettepe University
- Diseases
- Obesity
- NCT number
- NCT07513610
What you commit to
- Study type: Interventional
- Participants enrolled: 148
- From 24 Jan 2024 to the primary completion date, 17 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- To be using medication and/or nutritional supplements that can affect body weight
- To be using medication and/or nutritional supplements that can affect glycemic response
- To be using medication and/or nutritional supplements that can affect lipid profile
- To use medication and/or nutritional supplements that can affect intestinal microbiota composition (such as antibiotics, probiotics, prebiotics) in the last three months
Other illness
- To have a diagnosis of chronic and/or psychiatric illness
- To have diagnosis of celiac disease
- To have food allergies and/or food intolerances
Other
- To be using antibiotics
- To be a professional athlete
- To be pregnant or breastfeeding
- To be in postmenopausal period
- To have followed a specific diet aimed at reducing body weight in the last 6 months
- To regularly consume quinoa or buckwheat in the diet
- To be unable to continue with weekly interviews
- To show less than 80% compliance with the diet
- To not give consent for the research
Who the study is looking for
- Aged between 25 and 45
- Healthy People
- Having a body mass index between 25 and 35 kg/m²
Age in the registry: 25 years to 45 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hacettepe University Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.