NCT07515131Completed
Respiratory Function and S-index in Radiographic Axial Spondyloarthritis
Chest Expansion, Pulmonary Function, and Dynamic Inspiratory Muscle Strength (S-index) in Patients With Radiographic Axial Spondyloarthritis
Source: ClinicalTrials.gov · Last updated 7 Apr 2026
Brief summary (registry, in English)
Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory disease that may lead to reduced chest expansion and impaired respiratory function due to thoracic involvement. While inspiratory muscle strength is commonly assessed using maximum inspiratory pressure (MIP), the S-index is a novel parameter reflecting dynamic inspiratory muscle strength and has not yet been investigated in this population. This study aims to compare chest expansion, spirometric parameters, and S-index values between individuals with r-axSpA and healthy controls. Additionally, the relationships between these parameters and clinical indices (BASDAI, BASFI, and BASMI) will be evaluated in patients with r-axSpA. The study also aims to explore the potential role of the S-index in the assessment of pulmonary function in this patient group.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 52 (actual)
- First submitted
- 25 Mar 2026
- Start date
- 3 Jan 2025
- Primary completion date
- 28 Oct 2025
- Lead sponsor
- Gazi University
- Diseases
- Ankylosing spondylitis
- NCT number
- NCT07515131
What you commit to
- Study type: Observational
- Participants enrolled: 52
- From 3 Jan 2025 to the primary completion date, 28 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of known cardiopulmonary disease
- Presence of any rheumatologic disease other than radiographic axial spondyloarthritis (r-axSpA)
Other
- Inability to cooperate with testing procedures
- Presence of chest wall or spinal deformities that may restrict lung capacity (e.g., pectus carinatum, pectus excavatum, scoliosis)
- Professional athletes
Who the study is looking for
- Willingness to participate in the study and provide informed consent
- Age ≥18 years
- Absence of any known chronic disease (for the healthy control group)
- Diagnosis of radiographic axial spondyloarthritis according to the Assessment of SpondyloArthritis international Society (ASAS) criteria and absence of any additional chronic disease (for the r-axSpA group)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gazi University Hospital, Department of Physical Medicine and Rehabilitation Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.