NCT07515261Completed
pBFS Guided Neuromodulation Over DMPFC for ASD Treatment: Pilot Study
Repetitive Transcranial Magnetic Stimulation Guided by Personalized Brain Functional Sectors (pBFS) for Comorbid Autism Spectrum Disorder and Language Delay: an One-arm Pilot Study
Source: ClinicalTrials.gov · Last updated 7 Apr 2026
Brief summary (registry, in English)
This study will evaluate the feasibility and preliminary efficacy of pBFS-guided TMS treatment at DMPFC in autism spectrum disorder comorbid with language delay.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 22 (actual)
- First submitted
- 31 Mar 2026
- Start date
- 10 Mar 2023
- Primary completion date
- 27 Feb 2024
- Lead sponsor
- Changping Laboratory
- Diseases
- Autism
- NCT number
- NCT07515261
What you commit to
- Study type: Interventional
- Participants enrolled: 22
- From 10 Mar 2023 to the primary completion date, 27 Feb 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Received TMS, tCS, FUS, or other neuromodulation treatment in the last 3 months
Other illness
- Current or history of psychotic disorders, such as schizophrenia, schizoaffective disorder, bipolar disorder
- Current, history or family history of epilepsy
- Known severe physical diseases, such as congenital heart defect, traumatic brain injury
- Metal implantations, which are contradicted by MRI or TMS, such as artificial cardiac pacemakers, stents, cochlear implants
Other
- Severe self-injury or suicidal behavior presented in the last 1 year
- Severe visual, auditory, or motor disability that interferes with any study procedure
- Currently participating in other clinical trials
Who the study is looking for
- 6-30 years old
- Have the diagnosis of autism spectrum disorder
- ADOS-2 score is higher than the ASD cut-offs
- Have language development delay (the WISC-4 Verbal Comprehension Index lower than 70)
- Capacity to follow the study procedures, including fMRI scan under sedation, assessment, and rehabilitation training
- Participant's parents or other legal guardians give informed consent
Age in the registry: 6 years to 30 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| China Rehabilitation Research Center Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.