NCT07518290Recruiting
Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease
Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease: Protocol For a Double Blind Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 22 Sept 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if home-based temporal interference stimulation (TIS) works to improve motor symptoms in people with Parkinson's disease (PD). It will also learn about the safety of this treatment. The main questions it aims to answer are: 1. Does home-based TIS improve movement problems such as slow movement, stiffness, and walking difficulty? 2. Are the effects maintained after the treatment ends? 3. What medical problems (adverse events) occur during treatment? Researchers will compare active TIS to a sham treatment (a look-alike procedure that does not deliver active stimulation) to see if TIS works. Participants will: 1. Receive active TIS or sham stimulation once a day for 4 weeks at home under remote supervision 2. Visit the clinic at specific time points for movement assessments 3. Complete online questionnaires about symptoms and quality of life
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 98 (estimated)
- First submitted
- 30 Mar 2026
- Start date
- 4 Apr 2026
- Primary completion date
- 30 Jan 2028
- Lead sponsor
- Shanghai University of Sport
- Diseases
- Parkinson disease
- NCT number
- NCT07518290
What you commit to
- Study type: Interventional
- Planned participants: 98
- From 4 Apr 2026 to the primary completion date, 30 Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- diagnosis of other neurological conditions such as multiple sclerosis, previous stroke;
Other illness
- significant cognitive impairment as defined by the diagnosis of Alzheimer's disease or dementia, or Montreal Cognitive Assessment (MoCA) total score\<21, a recommended threshold for dementia in PD;
- physician-diagnosis of schizophrenia or other psychiatric illness;
Other
- contraindications to TIs (e.g., metal implantation, pacemakers, etc.);
- the use of DBS;
- report of severe lower-extremity arthritis, pain, or orthopedic problems significantly affecting gait;
- an unwillingness to cooperate or participate in the study protocol. Eligible and interested participants will then be enrolled and complete baseline assessments before the randomization.
Who the study is looking for
- Diagnosis of Parkinson's disease according to established clinical criteria
- Mild-to-moderate disease severity, defined as Hoehn and Yahr stage 1.5-3;
- Age between 40 and 80 years;
- Stable anti-parkinsonian medication regimen;
- Ability to walk unaided for at least 2 minutes.
Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shanghai University of Sport Coordinator of this site? Confirm its status | Shanghai | China | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.