NCT07519460Not yet recruiting
Effects of High-Frequency Chest Wall Oscillation Combined With Concurrent Training on Cough,in Cystic Fibrosis Patients
Effects of High-Frequency Chest Wall Oscillation Combined With Concurrent Training on Cough, Sputum, Exercise Tolerance and Respiratory Muscle Strength in Cystic Fibrosis Patients
Source: ClinicalTrials.gov · Last updated 9 Apr 2026
Brief summary (registry, in English)
This randomized clinical trial aims to evaluate the effects of high-frequency chest wall oscillation (HFCWO) combined with concurrent training on cough, sputum clearance, exercise tolerance, and respiratory muscle strength in patients with Cystic Fibrosis. A total of 24 participants meeting inclusion criteria will be randomly allocated into two groups: Group A will receive HFCWO plus concurrent training, while Group B will receive HFCWO alone for 8 weeks. Outcomes will be measured before and after intervention using the 6-minute walk test, spirometry, Leicester Cough Questionnaire, sputum volume, and the Cystic Fibrosis Questionnaire-Revised. The study will be conducted at Pulmonary Rehabilitation Unit, Gulab Devi Hospital and Mayo Hospital, Lahore. Statistical analysis will be performed using IBM SPSS Statistics, with significance set at p \< 0.05.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 2 Apr 2026
- Start date
- Apr 2026
- Primary completion date
- 28 May 2026
- Lead sponsor
- Riphah International University
- Diseases
- Cystic fibrosis
- NCT number
- NCT07519460
What you commit to
- Study type: Interventional
- Planned participants: 24
- From Apr 2026 to the primary completion date, 28 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute airway infection.
- Cognitive disorders affecting compliance.
- Cardiac diseases such as heart failure or arrhythmias.
- Neurological or orthopedic illnesses or recent chest injury.
Other
- Active hemoptysis or pneumothorax.
- Risk of hemodynamic instability or severe hypoxia.
- Pregnancy.
Who the study is looking for
- Diagnosed with Cystic Fibrosis, confirmed by genotype or sweat chloride \>60 mmol/L.
- Age 16-35 years.
- Both male and female participants.
- Stable clinical condition (no exacerbations in the last 2 weeks).
- Forced expiratory volume in 1 second (FEV₁ ≥ 20% predicted).
Age in the registry: 16 years to 35 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gulab Devi Hospital, Mayo Hospital Lahore. Coordinator of this site? Confirm its status | Lahore | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.