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NCT07519473Not yet recruiting

Neuromuscular Versus Resistance Training on Functional Capacity in Patients With Heart Failure.

Comparative Effects Between Neuromuscular Versus Resistance Training on Functional Capacity, Cardiorespiratory Fitness, and Lower Limb Performance in Patients With Heart Failure.

Source: ClinicalTrials.gov · Last updated 9 Apr 2026

Brief summary (registry, in English)

This randomized controlled trial will compare the effects of neuromuscular training and resistance training on functional capacity, cardiorespiratory fitness, and lower limb performance in patients with chronic heart failure. A total of 40 participants will be randomly assigned into two groups in a single-blinded design. Both groups will undergo a 10-week supervised exercise program. Outcomes will be assessed using VO₂ peak, 6-Minute Walk Test (6MWT), Short Physical Performance Battery (SPPB), and quality of life measures. The study aims to determine the more effective rehabilitation approach for improving clinical outcomes in heart failure patients.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
40 (estimated)
First submitted
2 Apr 2026
Start date
Apr 2026
Primary completion date
28 Jul 2026
Lead sponsor
Riphah International University
NCT number
NCT07519473

What you commit to

  • Study type: Interventional
  • Planned participants: 40
  • From Apr 2026 to the primary completion date, 28 Jul 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Absolute contraindications to exercise (e.g., recent MI, unstable angina, uncontrolled arrhythmias, severe aortic stenosis, decompensated HF)
  • Abnormal CPET findings (severe arrhythmias, ischemia, ST depression)
  • Exercise-induced angina or thoracic pain

Other

  • Abnormal blood pressure response during exercise
  • Musculoskeletal, neurological, or cognitive impairments limiting exercise participation

Who the study is looking for

  • Male and female patients aged 40-60 years
  • Diagnosed with chronic heart failure ≥ 1 year
  • Heart failure with reduced ejection fraction (HFrEF), EF ≤ 40%
  • NYHA Class II-III
  • Low to moderate exercise risk (based on Chester Step Test)
  • On stable pharmacological treatment for ≥ 6 weeks
  • Able to understand and follow exercise instructions

Age in the registry: 40 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
community based Cardiac Rehab Unit, Cardiac Centers, and Tertiary Care Hospitals
Coordinator of this site? Confirm its status
LahorePakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.