NCT07520448Not yet recruiting
Prevention and Mass Screening of TB in Prisons in Paraguay
Prevention and Mass Screening of TB in Prisons in Paraguay (PRESMAP-TB)
Source: ClinicalTrials.gov · Last updated 14 Apr 2026
Brief summary (registry, in English)
The goal of this interventional study is to evaluate three tuberculosis (TB) screening and prevention strategies in prisons in Paraguay. The main questions it aims to answer are: * Which strategy is more effective for reducing the incidence rate of active TB? * Which strategy is more effective for reducing the TB infection rate? * Are these strategies safe, feasible, and cost-effective in prison settings? Researchers will compare three cluster-based, non-randomized programmatic strategies implemented in three prisons. These strategies differ in the frequency of screening, the diagnostic methods used, and the approach to tuberculosis preventive therapy (TPT). Participants will: * undergo informed consent and clinical evaluation * receive TB screening through symptom assessment, chest digital X-ray with CAD, and rapid molecular testing, depending on site strategy * undergo IGRA testing and preventive therapy assessment, depending on the assigned strategy * be followed for 18 months, with screening rounds every 6 months or annually depending on the prison
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 4500 (estimated)
- First submitted
- 2 Apr 2026
- Start date
- 1 Aug 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Universidad Nacional de Caaguazu
- Diseases
- Tuberculosis
- NCT number
- NCT07520448
What you commit to
- Study type: Interventional
- Planned participants: 4500
- From 1 Aug 2026 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Are currently undergoing treatment for active tuberculosis at the time of the screening round.
- Have a medical condition that, in the opinion of the clinical staff, prevents the safe performance of the planned diagnostic procedures.
Who the study is looking for
- Be a person deprived of liberty (PDL) residing in one of the participating penitentiary centers during the study period.
- Be 18 years of age or older at the time of enrollment.
- Be present in the penitentiary facility at the time of a screening round or enter the facility during the study period.
- Provide informed consent to participate in the study.
Age in the registry: 18 years to 65 years · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidad Nacional de Caaguazú Coordinator of this site? Confirm its status | Coronel Oviedo | Paraguay | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.