NCT07524400Recruiting
Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
Effects of the Combination of Physical Exercise and Transcranial Direct Current Stimulation on Motor Function and Underlying Neurophysiological Mechanisms in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on motor function will be evaluated.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 2 Jan 2026
- Start date
- May 2026
- Primary completion date
- Aug 2026
- Lead sponsor
- Universidad Rey Juan Carlos
- Diseases
- Parkinson disease
- NCT number
- NCT07524400
What you commit to
- Study type: Interventional
- Planned participants: 100
- From May 2026 to the primary completion date, Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current treatment with cholinesterase inhibitors.
- Presence or prior implantation of a deep brain stimulation (DBS) device.
Other illness
- Significant cognitive impairment, defined as a score \< 23 on the Mini-Mental State Examination (MMSE).
- Presence of severe cardiovascular disease, including but not limited to:
- Congestive heart failure
- Ischemic heart disease
- Cardiac pacemaker
- Uncontrolled diabetes mellitus.
- History of stroke or traumatic brain injury.
- History of seizure disorder or epilepsy.
- History of major orthopedic surgery that could interfere with motor performance or gait.
- Presence of implanted electronic devices, including cardiac pacemakers, incompatible with study procedures.
Other
- Below-average premorbid intelligence, defined as a score \< 40 on the Vocabulary subtest of the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III).
- Clinically significant depression, defined as a score \> 10 on the Geriatric Depression Scale (GDS-15).
- Orthostatic hypotension
Who the study is looking for
- Clinical diagnosis of idiopathic Parkinson's disease, established according to the UK Parkinson's Disease Society Brain Bank Criteria.
- Ability to understand and comply with study procedures.
- Stable antiparkinsonian medication regimen prior to study participation.
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Center of Sport Research Coordinator of this site? Confirm its status | Fuenlabrada | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.