NCT07525271Not yet recruiting
Trial Phase: Syndemic Adapted Medly Uganda
An mHealth Implementation Strategy to Address the Syndemic of Mental Illness, Hypertension, and HIV in Uganda, Clinical Trial: Syndemic Adapted Medly Uganda (SAMU)
Source: ClinicalTrials.gov · Last updated 19 Aug 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the effectiveness of the Syndemic-Adapted Medly Uganda (SAMU) in improving mental health care among adults living with HIV and hypertension in Uganda. In sub-Saharan Africa (SSA), there is a high prevalence of depression and anxiety among people living with HIV (PLHIV) as well as alcohol use disorder (AUD). PLHIV who experience depression are less likely to link to HIV care, adhere to antiretroviral therapy, and achieve viral suppression. Building on research conducted to adapt Medly Uganda for mental health using a syndemic framework, this study aims to assess the effectiveness of SAMU on mental health screening and diagnosis. This will be accomplished through a two-arm trial in which 1. participants will be enrolled, screened, re-screened, and assessed for diagnosis and linkage to care for depression, anxiety and AUD and 2. evaluate the factors impacting sustained engagement in the SAMU program, through mixed methods.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 1500 (estimated)
- First submitted
- 6 Apr 2026
- Start date
- 1 Sept 2026
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- Yale University
- Diseases
- HIV, High blood pressure
- NCT number
- NCT07525271
What you commit to
- Study type: Interventional
- Planned participants: 1500
- From 1 Sept 2026 to the primary completion date, 31 Mar 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \>=18 years
Other
- No access to a mobile phone
- Inability to provide informed consent based on assessment by the onsite Research Assistant or HCW
- Healthcare Workers/Caregivers Criteria:
- Healthcare worker at participating site or caregiver for study participant at site
- Basic reading skills in one or more of the offered languages (English, Luganda) as determined by the Research Assistant
Who the study is looking for
- Patient at a participating HIV clinic site
- Currently living in Uganda with no intention of moving abroad in next 2 years
- Access to a mobile phone
- Basic reading skills in one or more of the offered languages (English, Luganda) as determined by the Research Assistant.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kawaala Hospital Coordinator of this site? Confirm its status | Kampala | Uganda | Unknown status |
| Naguru Hospital Coordinator of this site? Confirm its status | Kampala | Uganda | Unknown status |
| Nsambya Hospital Coordinator of this site? Confirm its status | Kampala | Uganda | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.