NCT07529145Recruiting
Cardiopulmonary Exercise Testing in Lung Cancer Patients Before and During Oncological Treatment
Assessment of Respiratory Parameters and Physical Performance in Patients With Lung Cancer Qualified for Oncological Treatment Before and During Therapy, With Special Consideration of Cardiovascular Risk: A Cardiopulmonary Exercise Testing Study
Source: ClinicalTrials.gov · Last updated 14 Apr 2026
Brief summary (registry, in English)
Patients with lung cancer often have reduced physical fitness and coexisting health problems, which may limit their ability to tolerate oncological treatment. Standard resting lung and heart tests do not always reflect real-life physical capacity during everyday activities or physical effort. This observational study aims to assess cardiorespiratory fitness in patients with lung cancer before and during standard oncological treatment using cardiopulmonary exercise testing (CPET). CPET is a safe, supervised exercise test that provides objective information on how the heart, lungs, and muscles respond to physical effort. Participants with WHO/ECOG performance status 0-2 will undergo CPET before treatment initiation and again after the early phase of therapy or surgery. The results may help identify patients with reduced physiological reserve and support individualized monitoring during routine clinical care.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 7 Apr 2026
- Start date
- 1 Jan 2026
- Primary completion date
- 1 Mar 2027
- Lead sponsor
- Medical University of Bialystok
- Diseases
- Lung cancer
- NCT number
- NCT07529145
What you commit to
- Study type: Observational
- Planned participants: 90
- From 1 Jan 2026 to the primary completion date, 1 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Unstable ischemic heart disease
- Symptomatic cardiac arrhythmias
- Decompensated heart failure
- Active deep vein thrombosis
- Any medical condition that, in the investigator's opinion, precludes safe participation in CPET
Other
- Myocarditis or pericarditis
- Suspected aortic dissection or severe aortic stenosis
- Poorly controlled asthma
- Resting oxygen saturation ≤ 85% on room air
- Clinically relevant treatment-related adverse events above mild intensity (as applicable)
- Withdrawal of informed consent
Who the study is looking for
- Age ≥ 18 years
- Histologically confirmed lung cancer (any stage)
- Qualified for standard oncological management (surgery and/or systemic therapy)
- WHO/ECOG performance status 0-2
- Ability to perform cardiopulmonary exercise testing (CPET)
- Written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Clinical Hospital in Bialystok, II Department of Pulmonology, Lung Cancer and Internal Medicine, Medical University of Bialystok Coordinator of this site? Confirm its status | Bialystok | Poland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.