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NCT07530354Recruiting

A Longitudinal Cohort Study on the Changes of Physiological Mechanisms in Children After Biliary Tract Reconstruction

Source: ClinicalTrials.gov · Last updated 15 Apr 2026

Brief summary (registry, in English)

Through observational studies, the long-term changes in liver function, metabolic state, immune response and other aspects of children after biliary tract reconstruction during their growth process were systematically explored. The risks of these long-term physiological changes on chronic diseases such as cardiovascular diseases, diabetic diseases and liver cirrhosis in adulthood, as well as their impacts on cognitive function, musculoskeletal health and other aspects were evaluated. How do early physiological changes affect a patient's long-term health? Are there any potential biomarkers that can predict future health outcomes? Based on the research results, preventive and intervention measures that are helpful in reducing the risk of long-term complications are proposed.

Status (registry)
Recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
22 Jun 2025
Start date
1 May 2025
Primary completion date
Apr 2035
Lead sponsor
Wuhan Children's Hospital
NCT number
NCT07530354

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 1 May 2025 to the primary completion date, Apr 2035
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Combined with other serious diseases (such as cancer, autoimmune diseases), having obvious liver function abnormalities before surgery or being undergoing other major treatments.

Who the study is looking for

  • Healthy children matched by age and gender were selected as the control group

Age in the registry: - to 16 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

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SiteCityCountrySite status
Wuhan Children's Hospital
Coordinator of this site? Confirm its status
WuhanChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.