NCT07530575Active, not recruiting
Limosilactobacillus Fermentum CRL 1446 - CONICET CASASCO
Biological Effects of the Consumption of Limosilactobacillus Fermentum CRL 1446 - CONICET in Volunteers With Cardiovascular Risk Factors
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
This research study aims to determine if a probiotic called Limosilactobacillus fermentum CRL 1446 can improve the health of people at risk for cardiovascular disease. The study will be conducted with volunteers who will randomly consume either the probiotic or a placebo (a capsule without the probiotic), without knowing which one they are taking. The researchers will analyze how the probiotic affects blood sugar control, body composition, inflammation, and oxidative stress. The goal is to determine if this beneficial bacterium, by influencing the gut microbiota, could be a new strategy to prevent or mitigate chronic heart diseases.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 28 Aug 2025
- Start date
- 2 Feb 2026
- Primary completion date
- 21 Jul 2027
- Lead sponsor
- PINER Pastor Manfredi Winery
- Diseases
- Obesity, High blood pressure, Type 2 diabetes
- NCT number
- NCT07530575
What you commit to
- Study type: Interventional
- Participants enrolled: 80
- From 2 Feb 2026 to the primary completion date, 21 Jul 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with a history of digestive surgeries, inflammatory bowel disease, patients with gastroenteritis in the last 6 months, cancer patients, patients with rheumatic pathologies, patients with liver disorders, immunological disorders or deficiencies, steatorrhea, antibiotic use in the last 3 months, or anemia of any cause or pregnancy/expectation of becoming pregnant during the study.
Other
- \-
Who the study is looking for
- Volunteers with the following conditions may be eligible:
- Blood glucose greater than 100 mg/dl or pharmacological treatment for high blood glucose levels;
- HDL cholesterol \< 40 mg/dl in men or \< 50 mg/dl in women, or pharmacological treatment for low HDL cholesterol levels;
- Blood triglycerides \> 150 mg/dl or pharmacological treatment for high triglyceride levels;
- Waist circumference \> 102 cm for men or \> 88 cm for women;
- Arterial pressure \> 130/85 mmHg;
- Sedentarism;
- Smoking habit.
Age in the registry: 40 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Raul Francisco Pastor Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Unknown status |
| TIEMPO MEDICO Health Research Center Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.