NCT07532473Not yet recruiting
REal World MAIA UK OutcomEs
A Retrospective Study of Clinical Outcomes in Newly Diagnosed, Transplant Ineligible Multiple Myeloma Patients Treated With Daratumumab, Lenalidomide and Dexamethasone (DRd) Outside of Clinical Trials in the UK
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
This study will describe the use of triplet therapy with daratumumab, lenalidomide and dexamethasone (DRd) in the treatment of for transplant ineligible (TIE) untreated myeloma outside of clinical trials and assess the associated clinical outcomes.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 7 Apr 2026
- Start date
- 1 Dec 2026
- Primary completion date
- 31 Jul 2028
- Lead sponsor
- The Royal Wolverhampton Hospitals NHS Trust
- Diseases
- Multiple myeloma
- NCT number
- NCT07532473
What you commit to
- Study type: Observational
- Planned participants: 300
- From 1 Dec 2026 to the primary completion date, 31 Jul 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participation in an interventional clinical trial for first-line therapy
Other illness
- DRd used in relapsed/refractory setting rather than newly diagnosed disease
Other
- Insufficient treatment or follow-up data for analysis
Who the study is looking for
- Age ≥18 years
- Diagnosis of NDMM
- Not eligible for autologous stem cell transplant at diagnosis
- Received frontline DRd treatment following NICE approval (post-September 2023)
- Minimum 3 months of follow-up data available
Age in the registry: 18 years to - · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Royal Wolverhampton NHS Trust Coordinator of this site? Confirm its status | Wolverhampton | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.