NCT07534254Active, not recruiting
Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program
Leveraging Generative Artificial Intelligence in Mobile Health Promotion Programs: A Use Case for Enhancing Tailored Messaging and Engagement in a Mobile Healthy Weight Program
Source: ClinicalTrials.gov · Last updated 26 Jun 2026
Brief summary (registry, in English)
The goal of this study is to learn if integrating a chatbot into an existing 12-week smartphone-delivered behavioral weight loss program is feasible and effective for weight loss among young adults. Researchers will compare a standard behavioral weight loss program for young adults that delivers 1-2 brief messages per day (AGILE) to the same program with a chatbot that offers additional behavior change support integrated into the app (AGILE + Chatbot) to determine if the program with the chatbot is feasible, acceptable to participants, and improves program engagement and weight change compared to AGILE alone.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 9 Apr 2026
- Start date
- 23 Mar 2026
- Primary completion date
- 21 Sept 2026
- Lead sponsor
- University of North Carolina, Chapel Hill
- Diseases
- Obesity
- NCT number
- NCT07534254
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 23 Mar 2026 to the primary completion date, 21 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Type 1 diabetes or currently receiving medical treatment for Type 2 diabetes
- Other health problems which may influence the ability to walk for physical activity or be associated with unintentional weight change, including tuberculosis, currently receiving cancer treatment, or history of a heart attack or stroke
- Currently taking weight loss medications
- Report a past diagnosis of, or receiving treatment for, a DSM-5-TR (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision) eating disorder (anorexia nervosa or bulimia nervosa)
Other illness
- Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q; items 1-4), or report any other reason not able to walk for physical activity
- History of weight loss surgery or planning weight loss surgery in the next 4 months
- Health or psychological diagnoses that preclude participation in a prescribed dietary and exercise program, including history of or diagnosis of schizophrenia or bipolar disorder, hospitalization for a psychiatric diagnosis in the past year, current diagnosis of alcohol or substance abuse
Other
- Lost 10 or more pounds (and kept it off) in the last 6 months
- Currently pregnant or planning to become pregnant within the next 4 months
- Another member of the household is a participant or staff member on this trial
- Currently participating in a weight loss, nutrition, or physical activity study or program or other study that would interfere with this study
- Not willing to wear a Fitbit every day
- Have participated in another study conducted by the UNC Weight Research Program within the past 12 months
Who the study is looking for
- body mass index (BMI) of 25-45 kg/m\^2
- English-speaking and writing
- own an iPhone with a data plan
- willing to be randomized to either treatment group
Age in the registry: 18 years to 39 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of North Carolina at Chapel Hill Coordinator of this site? Confirm its status | Chapel Hill | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.