NCT07536178Recruiting
Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in Canada
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While short-term breathing problems caused by smoke are well known, there is limited knowledge on how repeated exposure contributes to long-term lung disease. This study is a controlled human exposure to varying concentrations of WFS in a safe setting. By comparing the effects of different concentrations, this research will improve understanding of health impacts, identify who may be most vulnerable to exposures, and explore biological changes that could lead to chronic illness.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 3 Apr 2026
- Start date
- 26 May 2026
- Primary completion date
- 31 Aug 2029
- Lead sponsor
- University of British Columbia
- Diseases
- Asthma, COPD, Lung cancer
- NCT number
- NCT07536178
What you commit to
- Study type: Interventional
- Planned participants: 24
- From 26 May 2026 to the primary completion date, 31 Aug 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current smoker (within six months before screening; potential to confound exposure effects).
Other illness
- History or current diagnosis of any respiratory conditions (including, but not limited to asthma or chronic obstructive pulmonary disease (COPD), asthma/COPD overlap) or other medical conditions that the study physician determines may impact participant safety.
Other
- Any comorbidities or other concerns identified by the study physician which may impact study participation.
- For participants of child-bearing potential: Current pregnancy, or plans to become pregnant during study enrolment.
Who the study is looking for
- Healthy Adults between the ages of 19 to 80 (12 of each biological sex assigned at birth).
Age in the registry: 19 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Air Pollution Exposure Lab Coordinator of this site? Confirm its status | Vancouver | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.