NCT07539714Active, not recruiting
Development of an Active Heat Dissipation Device Based on Thermoelectric Cooling Technology: Aiming to Improve Endurance Sports Performance
Heat Acclimation and Innovative Cooling Systems: Optimizing Athletic Performance and Reducing Heat-Induced Performance Impairments in Hot Environments Under Climate Change Conditions
Source: ClinicalTrials.gov · Last updated 20 Apr 2026
Brief summary (registry, in English)
This project investigates the effectiveness of pre-exercise active cooling using a temperature-controlled cooling vest in reducing heat-related physiological strain during endurance-type aerobic exercise in non-regularly trained ("weekend") athletes under hot and humid environmental conditions. Because these individuals often lack sufficient heat-acclimation training, they are at increased risk of excessive thermal stress, cardiovascular overload, and heat-related disorders during prolonged exercise. Using a controlled laboratory design, participants will perform moderate-intensity endurance exercise in a simulated hot environment, with or without pre-cooling intervention. Peripheral circulation and thermoregulatory responses will be assessed through laser Doppler flowmetry based skin blood-flow analysis and infrared thermography, alongside heart rate and perceived exertion measures. The study aims to clarify how active pre-cooling influences vascular regulation, sympathetic activity, skin temperature distribution, and exercise tolerance, and to evaluate its potential as a practical, non-fatiguing alternative to heat-acclimation training. The findings are expected to provide evidence-based guidance for reducing heat strain and improving exercise safety and comfort in recreational endurance athletes exercising in hot climates.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 10 Feb 2026
- Start date
- 1 Feb 2026
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- Kaohsiung Medical University
- Diseases
- Stroke
- NCT number
- NCT07539714
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 1 Feb 2026 to the primary completion date, 28 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- • Diabetes, hypertension, or peripheral vascular disease.
- Long-term work in hot environments.
- BMI \> 30 kg/m², smoking, or heavy alcohol use.
- Allergic reactions triggered by heat or cold (e.g., hives).
Who the study is looking for
- Age 20-50 years.
- In the past 6 months, endurance exercise less than three times per week, 40-60 min each session.
- No cardiovascular, metabolic (e.g., diabetes), or neurological disorders, and no diseases affecting vascular regulation.
- No medication affecting vascular tone within the last 3 months.
- No major musculoskeletal injuries or disorders affecting performance within the last 3 months.
Age in the registry: 20 years to 50 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cooling Vest Coordinator of this site? Confirm its status | Kaohsiung City | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.