NCT07539844Recruiting
Study to Assess Prevalence of the Folate Receptor Alpha (FRa) in Adult Female Participants With Ovarian Cancer in Intercontinental (InterCon) Countries
A Concordance Study of Folate Receptor Alpha (FRa) Testing in InterCon Countries
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
Epithelial ovarian cancer (OC), including fallopian tube and primary peritoneal cancer, is the deadliest gynecologic malignant neoplasm with a 5-year relative survival of approximately 50%. This study will evaluate the concordance in folate receptor alpha (FRa) immunohistochemistry (IHC) in adult female participants with ovarian cancer. Archived tissue biopsies will be tested for FRa and data from approximately 1,000 participants will be collected. This is a retrospective study and testing will be performed prospectively on archived samples. Participants' charts will be reviewed. No drug will be administered as a part of this study. The duration of the study will be approximately 1 Year. There is no additional burden for participants in this trial.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 14 Apr 2026
- Start date
- 2 Jul 2026
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- AbbVie
- Diseases
- Ovarian cancer
- NCT number
- NCT07539844
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 2 Jul 2026 to the primary completion date, 31 Mar 2027
- 12 sites in 5 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Surgical or biopsy samples (FFPE) with insufficient quantity or quality (sampled more than 5 years ago and/or with less 100 viable tumor cells per section).
- Tissue obtained following treatment with Mirvetuximab soravtansine or any other FRa targeted therapy.
Other
- Tissue obtained through fine needle aspirations or liquid specimens, or ascites
Who the study is looking for
- Surgical or biopsy samples (Formalin Fixed Paraffin Embedded \[FFPE\]) with tumoral High Grade Serous Ovarian Cancer (HGSOC) material allowing the sectioning of serial slides for all the analyses.
- Archival specimens should not be older than 5 years in order to control quality of the samples.
- Specimens containing a minimum of 100 viable tumor cells.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (12)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Italiano de Buenos Aires /ID# 280315 Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Recruiting |
| Biomakers /ID# 280318 Coordinator of this site? Confirm its status | Buenos Aires | Argentina | Recruiting |
| Instituto Alexander Fleming /ID# 281479 Coordinator of this site? Confirm its status | Ciudad Autonoma de Buenos Aire | Argentina | Recruiting |
| Brazil - Generic Institution /ID# 287000 Coordinator of this site? Confirm its status | São Paulo | Brazil | Recruiting |
| A.C. Camargo Cancer Center - Rua Professor Antonio Prudente /ID# 280407 Coordinator of this site? Confirm its status | São Paulo | Brazil | Recruiting |
| Toronto General Hospital-University Health Network /ID# 282521 Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
| Instituto Nacional De Cancerologia /ID# 282312 Coordinator of this site? Confirm its status | Bogota | Colombia | Recruiting |
| Fundacion Para La Investigacion Clinica Y Molecular Aplicada Del Cancer - Ficmac /ID# 282327 Coordinator of this site? Confirm its status | Bogotá | Colombia | Recruiting |
| Fundacion Valle Del Lili /ID# 280794 Coordinator of this site? Confirm its status | Cali | Colombia | Recruiting |
| Mexico - Generic Institution /ID# 281930 Coordinator of this site? Confirm its status | Mexico City | Mexico | Recruiting |
| Mexico - Generic Institution /ID# 281928 Coordinator of this site? Confirm its status | Mexico City | Mexico | Recruiting |
| Mexico - Generic Institution /ID# 281927 Coordinator of this site? Confirm its status | Mexico City | Mexico | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.