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NCT07540403Recruiting

Survival Analysis in patiEnts With Bad Prognosis Epithelial Ovarian CArcinoma

Source: ClinicalTrials.gov · Last updated 20 Apr 2026

Brief summary (registry, in English)

Ovarian carcinoma is the most lethal gynecological malignancy. Epithelial ovarian carcinoma is the gynecological malignancy with the highest mortality rate. The prognosis of patients with recurrent disease is highly heterogeneous and is typically poor in cases of ovarian carcinoma with a progression-free survival (PFS) ≤ 6 months, for which therapeutic options are limited. However, it has been shown that patients with a PFS ≤ 6 months may not respond effectively to further treatments, whereas, conversely, patients with a PFS \> 6 months could still benefit from them. The classification of patients with recurrent disease has undergone continuous evolution over time. Essential factors to consider include patient characteristics, disease stage, and the precise genetic and molecular profile of the tumor. This study aims to evaluate survival in patients experiencing recurrence of epithelial ovarian carcinoma with an unfavorable prognosis, with the objective of improving patient categorization and management.

Status (registry)
Recruiting
Study type
Observational
Enrollment
50 (estimated)
First submitted
13 Mar 2025
Start date
24 Mar 2025
Primary completion date
1 Mar 2027
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
NCT number
NCT07540403

What you commit to

  • Study type: Observational
  • Planned participants: 50
  • From 24 Mar 2025 to the primary completion date, 1 Mar 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Criteria the registry did not label

  • INCLUSION CRITERIA
    • Patients diagnosed with histologically confirmed epithelial ovarian carcinoma, fallopian tube carcinoma, or primary peritoneal carcinoma with a PFS ≤6 months.
    • Age ≥18 years.
    • Any FIGO (Federation of Gynecology and Obstetrics) stage at diagnosis.
    • Signed informed consent for the use of personal data for research purposes.
    • ECOG performance status ≤2.
  • EXCLUSION CRITERIA
    • Age \<18 years.
    • Patients with non-epithelial ovarian carcinoma.
    • Patients with a PFS \>6 months.

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coordinator of this site? Confirm its status
RomeItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.