NCT07541729Active, not recruiting
Effect of Rosmarinus Officinalis Extract on Oxidative Stress and Inflammatory Biomarkers in Patients With Type 2 Diabetes (T2DM)
Randomized Controlled Trial Evaluating the Effect of Rosmarinus Officinalis Extract on Metabolic, Hepatic, Renal, Inflammatory, and Oxidative Stress Biomarkers in Patients With Type 2 Diabetes.
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
This randomized, placebo-controlled clinical trial evaluates the effects of a methanolic extract of Rosmarinus officinalis (rosemary) in patients with type 2 diabetes mellitus. Participants are randomly assigned to receive either methanolic rosemary extract or placebo in addition to their usual treatment and are followed for six months. A data cut-off at Month 3 is used for the analysis of metabolic, oxidative stress, and cytogenetic outcomes, while selected inflammatory and cardiovascular biomarkers continue to be assessed through Month 6. The study investigates the potential complementary effects of methanolic rosemary extract on metabolic control, oxidative stress, inflammation, genomic stability, and cardiovascular-related biomarkers in patients with type 2 diabetes mellitus.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 17 Mar 2026
- Start date
- 20 Sept 2025
- Primary completion date
- 1 Jun 2026
- Lead sponsor
- Universidad Autonoma de Zacatecas
- Diseases
- Type 2 diabetes
- NCT number
- NCT07541729
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 20 Sept 2025 to the primary completion date, 1 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who are taking other supplements or medications that may interfere with the study results. (antioxidants)
- 5\. Patients who are participating in another clinical trial simultaneously.
Other illness
- Allergy or hypersensitivity to any of the components of Rosemary.
Other
- Pregnant or breastfeeding women.
Who the study is looking for
- Confirmed diagnosis of T2DM
- Older adults over the age of 18.
- Signed Informed Consent (Annex 1)
- Clinical stability or absence of acute complications associated with diabetes or another disease at the time of the study.
- Absence of other associated diseases except Obesity and/or Hypertension
- Glomerular filtration rate greater than or equal to 60ml/min/1.73m2 according to the CKD-EPI 2021 formula
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ISSSTE (Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado) Coordinator of this site? Confirm its status | Zacatecas City | Mexico | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.