NCT07543666Recruiting
The ISAR InflEx Trial (Inflammation and Exercise)
Impact of Different Exercise Intensities and Durations on Systemic Inflammation - The ISAR InflEx Trial (Inflammation and Exercise) -
Source: ClinicalTrials.gov · Last updated 24 Apr 2026
Brief summary (registry, in English)
A sedentary lifestyle and obesity are associated with chronic low-grade inflammation and an elevated risk of cardiovascular disease (CVD). This study aims to systematically characterize and compare the effects of three distinct exercise modalities - moderate-intensity, vigorous-intensity, and short-duration maximal exercise - each differing in duration and intensity, on systemic inflammation and immune function. The study investigates the potential of exercise as an effective anti-inflammatory intervention for the prevention of CVD.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 33 (estimated)
- First submitted
- 15 Apr 2026
- Start date
- 1 Jan 2026
- Primary completion date
- Jun 2027
- Lead sponsor
- Department of Cardiology German Heart Center Munich TUM University Hospital
- Diseases
- Obesity
- NCT number
- NCT07543666
What you commit to
- Study type: Interventional
- Planned participants: 33
- From 1 Jan 2026 to the primary completion date, Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Regular use of medication
Other illness
- any acute or chronic illness
Other
- pregnancy and breastfeeding
- active smoking
Who the study is looking for
- BMI 25.0 - 30.0 kg/m²
- age 18 - 45 years
- informed consent
- no regular physical activity (≤1x/week of structured exercise)
- willingness to strictly follow and adhere to the intervention protocol for the entire study
Age in the registry: 18 years to 45 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| German Heart Centre Coordinator of this site? Confirm its status | München | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.