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NCT07545057Not yet recruiting

Robotic-Assisted Bronchoscopy-Guided Synchronous Biopsy and Radiofrequency Ablation for Pulmonary Nodules

A Feasibility Study on Synchronous Biopsy and Radiofrequency Ablation for Pulmonary Nodules Under Robotic-Assisted Bronchoscopy: A Prospective, Single-Arm, Open-Label Clinical Study:ROBUST Study

Source: ClinicalTrials.gov · Last updated 28 Apr 2026

Brief summary (registry, in English)

This is a prospective, single-arm, open-label clinical study. The primary study objective is to evaluate the feasibility of synchronous biopsy and radiofrequency ablation for pulmonary nodules under robotic-assisted bronchoscopy.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
76 (estimated)
First submitted
15 Apr 2026
Start date
1 May 2026
Primary completion date
30 Jun 2027
Lead sponsor
Shanghai Chest Hospital
NCT number
NCT07545057

What you commit to

  • Study type: Interventional
  • Planned participants: 76
  • From 1 May 2026 to the primary completion date, 30 Jun 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • The target nodule has been diagnosed as a malignant tumor or metastasis;
  • Severe pulmonary fibrosis and pulmonary hypertension;
  • Implanted cardiac pacemaker, defibrillator, or other electronic implants;
  • Other conditions that the investigators consider not suitable for the patient to participate in this study.

Lab values

  • Patients with severe bleeding tendency or uncorrectable coagulation disorder (platelet count \< 50×10\^9 /L, prothrombin time \> 18s, prothrombin activity \< 40%);
  • Anticoagulant or anti-platelet drugs have not been discontinued for the required time before surgery;

Age

  • Patients who cannot tolerate general anesthesia due to advanced age or severe cardiopulmonary diseases, or other reasons;

Other

  • Presence of important blood vessels that cannot be avoided along the biopsy path;

Who the study is looking for

  • Age ≥ 18 years old;
  • Chest CT indicates pulmonary nodules, highly suspected of being malignant;
  • Size of pulmonary nodules: 8 mm \< maximum diameter ≤ 30 mm, and the number of pulmonary nodules requiring intervention ≤ 3;
  • Preoperative imaging evaluation indicates no clear lymph node metastasis or distant metastasis (cT1N0M0);
  • Multidisciplinary evaluation shows that the patient cannot tolerate surgery and radiotherapy, or the patient refuses surgery and radiotherapy after full informed consent;
  • The patient understands and agrees to receive synchronous biopsy and ablation treatment under robotic-assisted bronchoscopy and signs a written informed consent form.

Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Shanghai Chest Hospital
Coordinator of this site? Confirm its status
ShanghaiChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.