NCT07545174Not yet recruiting
Role of the Environment in Pediatric Obesity
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
Childhood obesity is a particular concern in developed countries such as the United States, the United Kingdom, Canada, and certain European countries. According to the World Health Organization (WHO), approximately 6% of children under the age of 5 worldwide were obese in 2016, a figure that continues to rise. The pathophysiology of pediatric obesity can be explained by several interconnected biological and behavioral mechanisms. In particular, it involves dysfunctions in the hormones that regulate appetite and satiety, as well as dysfunctions in lipid metabolism. Per- and polyfluoroalkyl substances (PFAS) are a large family of synthetic chemical compounds. The main PFAS are perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), perfluorononanoic acid (PFNA), and perfluorohexanesulfonic acid (PFHxS). PFAS are present in many everyday consumer products. Bisphenol A (BPA) is a chemical compound used primarily in the manufacture of plastics and resins. It is commonly found in polycarbonate plastics, used to make food containers and water bottles, as well as in epoxy resins, which are used to coat the inside of food cans and water pipes. Non-persistent pesticides, such as organophosphates and polychlorinated biphenyls, are chemicals used primarily in agriculture to control insects and other pests. There are arguments suggesting that PFAS, bisphenol A, and non-persistent pesticides may play a role in the onset of pediatric obesity, particularly by acting.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 15 Apr 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 30 Jun 2029
- Lead sponsor
- University Hospital, Tours
- Diseases
- Obesity
- NCT number
- NCT07545174
What you commit to
- Study type: Interventional
- Planned participants: 80
- From 1 Jun 2026 to the primary completion date, 30 Jun 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Disorder preventing understanding of trial information or informed consent.
Who the study is looking for
- Patient with Obesity disorder :
- Children with obesity (according to the BMI curves of the International Obesity Task Force/IOTF)
- Follow-up within the obesity network of the Centre Val de Loire region (ObeCentre)
- Control group:
- Children who are not obese (according to the BMI curves of the International Obesity Task Force/IOTF)
- All:
- Children aged 6 to 15 at the time of inclusion (inclusive)
- Whose two parents, or legal guardian, have signed an informed consent form
- Patients affiliated with or covered by a social security system
Age in the registry: 6 years to 15 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHRU de Tours Coordinator of this site? Confirm its status | Tours | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.