NCT07545408Not yet recruiting
Subclinical Atherosclerosis in Juvenile Systemic Lupus Erythematosus
Subclinical Atherosclerosis in Juvenile Systemic Lupus Erythematosus: Evaluation by Carotid Intima-Media Thickness and Associated Cardiovascular Risk Factors
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
The aim of this study is to evaluate subclinical atherosclerosis in children and adolescents with juvenile SLE by measuring carotid intima-media thickness (CIMT), and to determine its associations with traditional cardiovascular risk factors (dyslipidemia, hypertension, obesity) and non-traditional disease-related risk factors (disease activity, lupus nephritis, corticosteroid dose, disease duration).
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 70 (estimated)
- First submitted
- 16 Apr 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- Assiut University
- Diseases
- Lupus (SLE)
- NCT number
- NCT07545408
What you commit to
- Study type: Observational
- Planned participants: 70
- From 1 Jun 2026 to the primary completion date, 1 Jun 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with other autoimmune or connective tissue overlap diseases (e.g., mixed connective tissue disease, juvenile dermatomyositis).
- Patients with congenital heart disease or known structural cardiovascular abnormalities.
- Patients with chronic kidney disease stage 4 or 5.
- Patients currently receiving lipid-lowering therapy prior to enrolment
Who the study is looking for
- \- Children and adolescents aged under 18 years diagnosed with JSLE according to the Systemic Lupus International Collaborating Clinics ( SLICC 2012 Criteria ).
- Disease duration of at least 6 months.
- Under regular follow-up at the study institution.
Age in the registry: 0 years to 18 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.