NCT07545629Completed
Epidemiology And Risk Factors Of Intradialytic Hypotension In Maintenance Hemodialysis Patients
Epidemiologic Characteristics And Risk Factors Of Intradialytic Hypotension In Maintenance Hemodialysis Patients: A Prospective Multicenter Cross-sectional Study
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
This prospective, multicenter observational study aims to describe how often intradialytic hypotension (IDH) occurs and to identify its risk factors in adult patients receiving maintenance hemodialysis. Intradialytic hypotension is a common complication during dialysis that can lead to symptoms, organ hypoperfusion, and interruption of treatment. Participants will be adults on regular maintenance hemodialysis who meet predefined inclusion and exclusion criteria. Routine clinical information will be collected, including demographics, primary kidney disease, comorbidities, medications, dialysis vintage, dialysis prescription (ultrafiltration volume and rate, dialysate composition, treatment time), and standard laboratory tests. During a defined observation period, blood pressure and related symptoms will be recorded across dialysis sessions to document the frequency, severity, and patterns of IDH. The main goals are to estimate the incidence and prevalence of intradialytic hypotension in maintenance hemodialysis patients and to explore potential risk factors, such as patient characteristics, cardiovascular status, volume status, and dialysis-related parameters. The findings may help clinicians better recognize patients at high risk of IDH and optimize dialysis prescriptions and monitoring strategies to reduce the occurrence of IDH and its adverse consequences.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 395 (actual)
- First submitted
- 15 Apr 2026
- Start date
- Feb 2025
- Primary completion date
- Feb 2025
- Lead sponsor
- First Affiliated Hospital of Wannan Medical College
- Diseases
- Chronic kidney disease
- NCT number
- NCT07545629
What you commit to
- Study type: Observational
- Participants enrolled: 395
- From Feb 2025 to the primary completion date, Feb 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pre-dialysis systolic blood pressure \<90 mmHg on the study day before starting dialysis
Other illness
- Acute medical instability precluding observation of a routine dialysis session (e.g., active sepsis requiring vasopressors, uncontrolled arrhythmias)
- Recent acute coronary syndrome or stroke within 3 months
- Ongoing active major bleeding or anticipated urgent transfusion during the session
Other
- Pregnancy
- Participation in an interventional trial expected to alter intradialytic blood pressure during the observed session
Who the study is looking for
- Adults (≥18 years) with end-stage renal disease on maintenance hemodialysis
- Receiving thrice-weekly (or routine) in-center hemodialysis for ≥3 months before enrollment
- Scheduled for a standard hemodialysis session of approximately 3-5 hours on the study day
- Able to provide informed consent (or via legally authorized representative, if applicable)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College) Coordinator of this site? Confirm its status | Wuhu | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.