NCT07546318Completed
PENS vs TENS for Hand Function in Multiple Sclerosis
Percutaneous Versus Transcutaneous Nerve Stimulation of the Median, Radial, and Ulnar Nerves: Effects on Hand Function in Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 22 Apr 2026
Brief summary (registry, in English)
This randomized, parallel, single-blind clinical trial aims to compare the immediate and short-term effects of percutaneous electrical nerve stimulation (PENS) versus transcutaneous electrical nerve stimulation (TENS), applied simultaneously to the median, radial, and ulnar nerves, on hand function in people with multiple sclerosis. Participants will be assessed at baseline, immediately after the intervention, and 72 hours later. Outcomes include fine manual dexterity, gross manual dexterity, pinch strength, and tactile sensitivity.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 28 (actual)
- First submitted
- 15 Apr 2026
- Start date
- 1 Jan 2026
- Primary completion date
- 15 Mar 2026
- Lead sponsor
- Universidad de Burgos
- Diseases
- Multiple sclerosis
- NCT number
- NCT07546318
What you commit to
- Study type: Interventional
- Participants enrolled: 28
- From 1 Jan 2026 to the primary completion date, 15 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent relapse or any concomitant neurological condition that could interfere with study participation or evaluation.
Other illness
- Musculoskeletal disorders or injuries affecting the upper limb.
- Skin lesions or dermatological conditions at the stimulation sites.
- Cognitive impairment that interferes with understanding or performing the assessments.
Other
- Implanted electrical devices.
Who the study is looking for
- Diagnosis of multiple sclerosis according to McDonald criteria.
- Age between 18 and 80 years.
- Clinically stable for at least 2 months before enrollment.
- No recent corticosteroid treatment.
- Functional ability to complete the study assessments, defined as a Nine Hole -Peg Test time of less than 300 seconds and the ability to transfer at least 1 block in the Box and Block Test.
- Ability to understand the study procedures and provide written informed consent.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Burgos Coordinator of this site? Confirm its status | Burgos | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.