NCT07547722Active, not recruiting
Effect of a High-Protein Diet With Meal Replacements on Weight Loss
Evaluation of the Effectiveness of a High-Protein Diet With Meal Replacement and Dietary Supplementation in a Weight Management Program
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if a structured high-protein diet with meal replacements can help with weight loss in adults with overweight or obesity. The main questions it aims to answer are: Does this diet help participants lose more body weight? Does this diet improve body composition and blood markers such as glucose and cholesterol? Researchers will compare a structured diet program with meal replacements to a standard low-calorie diet to see if it leads to better weight loss and health outcomes. Participants will: Follow a calorie-restricted diet for the duration of the study Be assigned to either a meal replacement program or a standard diet Attend study visits for body measurements and blood tests Report their feelings of hunger and fullness
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 17 Apr 2026
- Start date
- 1 Apr 2026
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- Kazakh Academy of Nutrition
- Diseases
- Obesity
- NCT number
- NCT07547722
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 1 Apr 2026 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe or uncontrolled cardiovascular disease, including recent myocardial infarction or stroke within the past 6 months, unstable angina, or heart failure
- Uncontrolled arterial hypertension at screening
- Severe renal impairment
- Diabetes requiring insulin therapy or uncontrolled diabetes
- Active oncological disease or cancer treatment within the past 12 months
- Acute or chronic inflammatory disease in the acute stage
- History of gastrointestinal or bariatric surgery affecting absorption or body weight within the past 12 months
Lab values
- Severe pulmonary disease in the stage of decompensation Allergy or intolerance to components of the study products, including milk proteins or lactose-containing products Current use of medications or dietary supplements that significantly affect body weight, if discontinuation before study start is not possible Participation in another interventional clinical study within the past 3 months Inability to provide informed consent or comply with the study protocol Significant body weight change, defined as more than 5% gain or loss, within the past 3 months before screening Severe psychiatric disorders or eating disorders that may interfere with participation Active alcohol or substance dependence Chronic use of systemic glucocorticoids or other medications affecting body weight, if discontinuation is not appropriate Planned pregnancy during the study period Uncontrolled thyroid disease Acute infection or febrile illness at screening Clinically significant abnormal laboratory findings at screening that, in the investigator's opinion, make participation unsafe
Other
- Pregnancy or breastfeeding
- Women of reproductive potential who are not using reliable contraception during the study
- Severe hepatic dysfunction
Who the study is looking for
- Adults aged 25 to 60 years
- Overweight or obesity
- Ability to provide informed consent
- Willingness to follow a calorie-restricted diet program
- Willingness to comply with study procedures
Age in the registry: 25 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kazakh Academy of Nutrition LLP Coordinator of this site? Confirm its status | Almaty | Kazakhstan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.